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Exploring the role of EMT in Ovarian Cancer Progression: Insights from a multiscale mathematical model
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2024
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S. Oliver
Michael E. Williams
Mohit Kumar Jolly
Deyarina GonzĂĄlez
Gibin Powathil
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Dynamic phenotypic switching and group behavior help non-small cell lung cancer cells evade chemotherapy
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2024
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Arin Nam
Atish Mohanty
S. Bhattacharya
Sourabh Kotnala
Srisairam Achuthan
Kishore Hari
Saumya Srivastava
Linlin Guo
Anusha Nathan
Rishov Chatterjee
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Dynamic Plasticity Systems Direct Early Adaptation to Treatment in Neuroblastoma
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2023
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Cecilia Roux
SiĂąn Hamer
Abigail Shea
Emilia Chen
Ayeh Sadat Sadr
Christie English
Sarthak Sahoo
Alejandro Allo Anido
Harvey Che
Louis Chesler
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Cell-state transitions and frequency-dependent interactions among subpopulations together explain the dynamics of spontaneous epithelial-mesenchymal heterogeneity in breast cancer
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2023
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Paras Jain
Ramanarayanan Kizhuttil
M Nair
Sugandha Bhatia
Erik W. Thompson
Jason T. George
Mohit Kumar Jolly
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Spatial heterogeneity in tumor adhesion qualifies collective cell migration
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2023
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Chinmayi Prasanna
Mohit Kumar Jolly
Ramray Bhat
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Dynamical modeling of proliferative-invasive plasticity and IFNÎł signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
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2023
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Seemadri Subhadarshini
Sarthak Sahoo
Shibjyoti Debnath
Jason A. Somarelli
Mohit Kumar Jolly
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Theoretical and computational tools to model multistable gene regulatory networks
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2023
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Federico Bocci
Dongya Jia
Qing Nie
Mohit Kumar Jolly
José N. Onuchic
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Link updating strategies influence consensus decisions as a function of the direction of communication
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2023
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Sharaj Kunjar
Ariana StrandburgâPeshkin
Helge Giese
Pranav Minasandra
Sumantra Sarkar
Mohit Kumar Jolly
Nico Gradwohl
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Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation
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2023
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Frederick R. Adler
Alexander R.A. Anderson
Abhinav Bhushan
Paul Bogdan
Jose Javier BravoâCordero
Amy Brock
Yun Chen
Edna Cukierman
Kathleen E. DelGiorno
Gerald V. Denis
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Supplementary Data from A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
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2023
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Federico Bocci
Mohit Kumar Jolly
JosĂš N. Onuchic
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Data from A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
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2023
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Federico Bocci
Mohit Kumar Jolly
JosĂš N. Onuchic
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Data from A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
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2023
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Federico Bocci
Mohit Kumar Jolly
JosĂš N. Onuchic
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Supplementary Data from A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
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2023
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Federico Bocci
Mohit Kumar Jolly
José N. Onuchic
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Dynamical modelling of proliferative-invasive plasticity and IFNÎł signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
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2023
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Seemadri Subhadarshini
Sarthak Sahoo
Shibjyoti Debnath
Jason A. Somarelli
Mohit Kumar Jolly
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Theoretical and computational tools to model multistable gene regulatory networks
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2023
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Federico Bocci
Dongya Jia
Qing Nie
Mohit Kumar Jolly
José N. Onuchic
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An integrative phenotype-structured partial differential equation model for the population dynamics of epithelial-mesenchymal transition
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2023
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Jules Guilberteau
Paras Jain
Mohit Kumar Jolly
Camille Pouchol
Nastassia Pouradier Duteil
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Spatio-temporal pattern formation due to host-circuit interplay in gene expression dynamics
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2022
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Priya Chakraborty
Mohit Kumar Jolly
Ushasi Roy
Sayantari Ghosh
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Spatio-temporal Pattern Formation due to Host-Circuit Interplay in Gene Expression Dynamics
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2022
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Priya Chakraborty
Mohit Kumar Jolly
Ushasi Roy
Sayantari Ghosh
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Stochastic population dynamics of cancer stemness and adaptive response to therapies
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2022
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Paras Jain
Atchuta Srinivas Duddu
Mohit Kumar Jolly
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Robustness in phenotypic plasticity and heterogeneity patterns enabled by EMT networks
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2022
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Anish Hebbar
Ankush Moger
Kishore Hari
Mohit Kumar Jolly
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Stochastic Population Dynamics of Cancer Stemness and Adaptive Response to Therapies
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2022
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Paras Jain
Atchuta Srinivas Duddu
Mohit Kumar Jolly
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Cancer: More than a geneticistâs Pandoraâs box
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2022
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Kritika Saxena
Ayalur Raghu Subbalakshmi
Prakash Kulkarni
Mohit Kumar Jolly
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Roadmap on plasticity and epigenetics in cancer
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2022
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Jasmine Foo
David Basanta
Russell C. Rockne
Carly Strelez
Curran Shah
Kimya Ghaffarian
Shannon M. Mumenthaler
Kelly Mitchell
Justin D. Lathia
David Frankhouser
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Biophysical and Biochemical mechanisms underlying Collective Cell Migration in Cancer Metastasis
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2022
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Ushasi Roy
Tyler Collins
Mohit Kumar Jolly
Parag Katira
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Spatio-temporal Pattern Formation due to Host-Circuit Interplay in Gene Expression Dynamics
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2022
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Priya Chakraborty
Ushasi Roy
Mohit Kumar Jolly
Sayantari Ghosh
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Link updating strategies influence consensus decisions as a function of the direction of communication
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2022
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Sharaj Kunjar
Ariana StrandburgâPeshkin
Helge Giese
Sumantra Sarkar
Mohit Kumar Jolly
Nico Gradwohl
|
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PDF
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Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy
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2021
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Arin Nam
Atish Mohanty
S. Bhattacharya
Sourabh Kotnala
Srisairam Achuthan
Kishore Hari
Saumya Srivastava
Linlin Guo
Anusha Nathan
Rishov Chatterjee
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Cancer: More Than a Geneticistâs Pandoraâs Box
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2021
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Kritika Saxena
Ayalur Raghu Subbalakshmi
Prakash Kulkarni
Mohit Kumar Jolly
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Matrix adhesion and remodeling diversifies modes of cancer invasion across spatial scales
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2021
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D. Pramanik
Mohit Kumar Jolly
Ramray Bhat
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Towards decoding the coupled decision-making of metabolism and epithelial-to-mesenchymal transition in cancer
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2021
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Dongya Jia
Jun Hyoung Park
Harsimran Kaur
Kwang Hwa Jung
Sukjin Yang
Shubham Tripathi
Madeline Galbraith
Youyuan Deng
Mohit Kumar Jolly
Benny Abraham Kaipparettu
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A mechanistic model captures the emergence and implications of non-genetic heterogeneity and reversible drug resistance in ER+ breast cancer cells
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2021
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Sarthak Sahoo
Ashutosh Mishra
Harsimran Kaur
Kishore Hari
Srinath Muralidharan
Susmita Mandal
Mohit Kumar Jolly
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Coupled Feedback Loops Involving PAGE4, EMT and Notch Signaling Can Give Rise to Non-Genetic Heterogeneity in Prostate Cancer Cells
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2021
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Divyoj Singh
Federico Bocci
Prakash Kulkarni
Mohit Kumar Jolly
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Group Behavior and Emergence of Cancer Drug Resistance
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2021
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S. Bhattacharya
Atish Mohanty
Srisairam Achuthan
Sourabh Kotnala
Mohit Kumar Jolly
Prakash Kulkarni
Ravi Salgia
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Editorial: Characterizing the Multi-Faceted Dynamics of Tumor Cell Plasticity
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2021
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S. C. Tripathi
Mohit Kumar Jolly
Sendurai A. Mani
Herbert Levine
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Coupled feedback loops involving PAGE4, EMT and Notch signaling can give rise to non-genetic heterogeneity in prostate cancer cells
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2020
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Divyoj Singh
Federico Bocci
Prakash Kulkarni
Mohit Kumar Jolly
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Hybrid E/M Phenotype(s) and Stemness: A Mechanistic Connection Embedded in Network Topology
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2020
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Satwik Pasani
Sarthak Sahoo
Mohit Kumar Jolly
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Hybrid E/M phenotype(s) and stemness: a mechanistic connection embedded in network topology
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2020
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Satwik Pasani
Sarthak Sahoo
Mohit Kumar Jolly
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The Good, The Bad and The Ugly: A Mathematical Model Investigates the Differing Outcomes Among CoVID-19 Patients
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2020
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Sarthak Sahoo
Siddharth Jhunjhunwala
Mohit Kumar Jolly
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Anticipating the Novel Coronavirus Disease (COVID-19) Pandemic
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2020
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Taranjot Kaur
Sukanta Sarkar
Sourangsu Chowdhury
Sudipta Kumar Sinha
Mohit Kumar Jolly
Partha Sharathi Dutta
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Understanding the Principles of Pattern Formation Driven by Notch Signaling by Integrating Experiments and Theoretical Models
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2020
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Federico Bocci
José N. Onuchic
Mohit Kumar Jolly
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Identifying inhibitors of epithelialâmesenchymal plasticity using a network topology-based approach
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2020
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Kishore Hari
Burhanuddin Sabuwala
Balaram Vishnu Subramani
Caterina A. M. La Porta
Stefano Zapperi
Francesc Font-Clos
Mohit Kumar Jolly
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Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomes
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2020
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Sarthak Sahoo
Kishore Hari
Siddharth Jhunjhunwala
Mohit Kumar Jolly
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Understanding the principles of pattern formation driven by Notch signaling by integrating experiments and theoretical models
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2020
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Federico Bocci
José N. Onuchic
Mohit Kumar Jolly
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Interactive dynamics of matrix adhesion and reaction-diffusion predict diverse multiscale strategies of cancer cell invasion
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2020
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Durjay Pramanik
Mohit Kumar Jolly
Ramray Bhat
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Anticipating the novel coronavirus disease (COVID-19) pandemic
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2020
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Taranjot Kaur
Sukanta Sarkar
Sourangsu Chowdhury
Sudipta Kumar Sinha
Mohit Kumar Jolly
Partha Sharathi Dutta
|
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PDF
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Phenotypic switching and adaptive strategies of cancer cells in response to stress: insights from live cell imaging and mathematical modeling
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2020
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Arin Nam
Atish Mohanty
S. Bhattacharya
Sourabh Kotnala
Srisairam Achuthan
Kishore Hari
Anusha Nathan
Govindan Rangarajan
Erminia Massarelli
Herbert Levine
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Suppressing chemoresistance in lung cancer via dynamic phenotypic switching and intermittent therapy
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2020
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Arin Nam
Atish Mohanty
S. Bhattacharya
Sourabh Kotnala
Srisairam Achuthan
Kishore Hari
Anusha Nathan
Govindan Rangarajan
Erminia Massarelli
Herbert Levine
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A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
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2020
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Shubham Tripathi
Priyanka Chakraborty
Herbert Levine
Mohit Kumar Jolly
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The Physics of Cellular Decision Making During EpithelialâMesenchymal Transition
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2020
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Shubham Tripathi
Herbert Levine
Mohit Kumar Jolly
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Towards decoding the coupled decision-making of metabolism and epithelial-mesenchymal transition in cancer
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2020
|
Dongya Jia
Jun Hyoung Park
Harsimran Kaur
Kwang Hwa Jung
Sukjin Yang
Shubham Tripathi
Madeline Galbraith
Youyuan Deng
Mohit Kumar Jolly
Benny Abraham Kaipparettu
|
+
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Dynamic Phenotypic Switching and Group Behavior Help Cancer Cells Evade Chemotherapy
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2020
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Arin Nam
Atish Mohanty
S. Bhattacharya
Sourabh Kotnala
Srisairam Achuthan
Kishore Hari
Saumya Srivastava
Linlin Guo
Anusha Nathan
Rishov Chatterjee
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+
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Interactive Dynamics of Reaction-Diffusion and Adhesion Predict Diverse Invasion Strategies of Cancer Cells in Matrix-Like Microenvironments
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2020
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Durjay Pramanik
Mohit Kumar Jolly
Ramray Bhat
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Understanding the principles of pattern formation driven by Notch signaling by integrating experiments and theoretical models
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2020
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Federico Bocci
José N. Onuchic
Mohit Kumar Jolly
|
+
PDF
Chat
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A Biophysical Model Uncovers the Size Distribution of Migrating Cell Clusters across Cancer Types
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2019
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Federico Bocci
Mohit Kumar Jolly
José N. Onuchic
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+
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Mathematical Modeling of Plasticity and Heterogeneity in EMT.
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2019
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Shubham Tripathi
Jianhua Xing
Herbert Levine
Mohit Kumar Jolly
|
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PDF
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Quantifying Cancer Epithelial-Mesenchymal Plasticity and its Association with Stemness and Immune Response
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2019
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Dongya Jia
Xuefei Li
Federico Bocci
Shubham Tripathi
Youyuan Deng
Mohit Kumar Jolly
José N. Onuchic
Herbert Levine
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Quantifying Cancer Epithelial-Mesenchymal Plasticity and Its Association with Stemness and Immune Response
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2019
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Dongya Jia
Xuefei Li
Federico Bocci
Shubham Tripathi
Youyuan Deng
Mohit Kumar Jolly
José N. Onuchic
Herbert Levine
|
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A Mechanism for Epithelial-Mesenchymal Heterogeneity in a Population of Cancer Cells
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2019
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Shubham Tripathi
Herbert Levine
Mohit Kumar Jolly
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Deciphering the Dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in Tumor Progression
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2019
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Federico Bocci
Herbert Levine
José N. Onuchic
Mohit Kumar Jolly
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Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment
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2019
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Xuefei Li
Mohit Kumar Jolly
Jason T. George
Kenneth J. Pienta
Herbert Levine
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Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response
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2019
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Dongya Jia
Xuefei Li
Federico Bocci
Shubham Tripathi
Youyuan Deng
Mohit Kumar Jolly
José N. Onuchic
Herbert Levine
|
+
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Mathematical Modeling of Plasticity and Heterogeneity in EMT
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2019
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Shubham Tripathi
Jianhua Xing
Herbert Levine
Mohit Kumar Jolly
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+
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Stability and mean residence times for hybrid epithelial/mesenchymal phenotype
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2018
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Kuheli Biswas
Mohit Kumar Jolly
Anandamohan Ghosh
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Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment
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2018
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Xuefei Li
Mohit Kumar Jolly
Jason T. George
Kenneth J. Pienta
Herbert Levine
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Towards understanding cancer stem cell heterogeneity in the tumor microenvironment
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2018
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Federico Bocci
Larisa Gearhart-Serna
Marcelo Boareto
Mariana P.C. Ribeiro
Eshel BenâJacob
Gayathri R. Devi
Herbert Levine
José N. Onuchic
Mohit Kumar Jolly
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Deciphering the dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in tumor progression.
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2018
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Federico Bocci
Herbert Levine
José N. Onuchic
Mohit Kumar Jolly
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Analysis of Hierarchical Organization in Gene Expression Networks Reveals Underlying Principles of Collective Tumor Cell Dissemination and Metastatic Aggressiveness of Inflammatory Breast Cancer
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2018
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Shubham Tripathi
Mohit Kumar Jolly
Wendy A. Woodward
Herbert Levine
Michael W. Deem
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Deciphering the dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in tumor progression
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2018
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Federico Bocci
Herbert Levine
José N. Onuchic
Mohit Kumar Jolly
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Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer
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2017
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Shubham Tripathi
Mohit Kumar Jolly
Wendy A. Woodward
Herbert Levine
Michael W. Deem
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Distinguishing mechanisms underlying EMT tristability
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2017
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Dongya Jia
Mohit Kumar Jolly
S. C. Tripathi
Petra den Hollander
Bin Huang
Mingyang Lu
MĂŒge ĂeliktaĆ
Esmeralda RamirezâPeña
Eshel BenâJacob
José N. Onuchic
|
+
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Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer
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2017
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Shubham Tripathi
Mohit Kumar Jolly
Wendy A. Woodward
Herbert Levine
Michael W. Deem
|
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Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
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2017
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Mohit Kumar Jolly
S. C. Tripathi
Jason A. Somarelli
Samir Hanash
Herbert Levine
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+
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Epithelial-mesenchymal plasticity: How have quantitative mathematical models helped improve our understanding?
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2017
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Mohit Kumar Jolly
S. C. Tripathi
Jason A. Somarelli
Samir Hanash
Herbert Levine
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Computational systems biology of epithelial-hybrid-mesenchymal transitions
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2017
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Mohit Kumar Jolly
Herbert Levine
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PDF
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Distinguishing Mechanisms Underlying EMT Tristability
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2017
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Dongya Jia
Mohit Kumar Jolly
S. C. Tripathi
Petra den Hollander
Bin Huang
Mingyang Lu
MĂŒge ĂeliktaĆ
Esmeralda RamirezâPeña
Eshel BenâJacob
José N. Onuchic
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+
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Distinguishing Mechanisms Underlying EMT Tristability
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2017
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Dongya Jia
Mohit Kumar Jolly
S. C. Tripathi
Petra den Hollander
Bin Huang
Mingyang Lu
MĂŒge ĂeliktaĆ
Esmeralda RamirezâPeña
Eshel BenâJacob
José N. Onuchic
|
+
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Analysis of hierarchical organization in gene expression networks reveals underlying principles of collective tumor cell dissemination and metastatic aggressiveness of inflammatory breast cancer
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2017
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Shubham Tripathi
Mohit Kumar Jolly
Wendy A. Woodward
Herbert Levine
Michael W. Deem
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Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
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2015
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Mohit Kumar Jolly
Marcelo Boareto
Bin Huang
Dongya Jia
Mingyang Lu
José N. Onuchic
Herbert Levine
Eshel BenâJacob
|
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Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
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2015
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Mohit Kumar Jolly
Marcelo Boareto
Bin Huang
Dongya Jia
Mingyang Lu
Eshel BenâJacob
José N. Onuchic
Herbert Levine
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Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
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2015
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Mohit Kumar Jolly
Marcelo Boareto
Bin Huang
Dongya Jia
Mingyang Lu
José N. Onuchic
Herbert Levine
Eshel BenâJacob
|
+
PDF
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Biophysical and Biochemical Mechanisms Underlying Collective Cell Migration in Cancer Metastasis
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2012
|
Ushasi Roy
Tyler A. Collins
Mohit Kumar Jolly
Parag Katira
|