Multistability in the epithelial-mesenchymal transition network
Multistability in the epithelial-mesenchymal transition network
Abstract Background The transitions between epithelial (E) and mesenchymal (M) cell phenotypes are essential in many biological processes like tissue development and cancer metastasis. Previous studies, both modeling and experimental, suggested that in addition to E and M states, the network responsible for these phenotypes exhibits intermediate phenotypes between E …