Tumor Invasion Optimization by Mesenchymal-Amoeboid Heterogeneity
Tumor Invasion Optimization by Mesenchymal-Amoeboid Heterogeneity
Abstract Metastasizing tumor cells migrate through the surrounding tissue and extracellular matrix toward the blood vessels, in order to colonize distant organs. They typically move in a dense environment, filled with other cells. In this work we study cooperative effects between neighboring cells of different types, migrating in a maze-like …