Prefer a chat interface with context about you and your work?
Phenotypic switching and adaptive strategies of cancer cells in response to stress: insights from live cell imaging and mathematical modeling
The impact of group behaviour on drug resistance in cancer remains poorly understood. We used fluorescently-tagged cisplatin-sensitive and tolerant lung cancer cells grown as monotypic or heterotypic cultures in the absence or presence of cisplatin, and monitored their behaviour and growth in real time. Competition and cooperation were modeled by …