Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
Phenotypic plasticity, the ability of cells to reversibly alter their phenotypes in response to signals, presents a significant clinical challenge to treating solid tumors. Tumor cells utilize phenotypic plasticity to evade therapies, metastasize, and colonize distant organs. As a result, phenotypic plasticity can accelerate tumor progression. A well‐studied example of …