Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach
Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach
Metastasis is the cause of over 90% of cancer-related deaths. Cancer cells undergoing metastasis can switch dynamically between different phenotypes, enabling them to adapt to harsh challenges, such as overcoming anoikis and evading immune response. This ability, known as phenotypic plasticity, is crucial for the survival of cancer cells during …