A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
Epithelial-mesenchymal heterogeneity implies that cells within the same tumor can exhibit different phenotypesā€”epithelial, mesenchymal, or one or more hybrid epithelial-mesenchymal phenotypes. This behavior has been reported across cancer types, both in vitro and in vivo, and implicated in multiple processes associated with metastatic aggressiveness including immune evasion, collective dissemination of ā€¦