Kevin Leder

Generating author description...

All published works

Action	Title	Year	Authors
+	Parameter estimation from single patient, single time-point sequencing data of recurrent tumors	2024	Kevin Leder Ruping Sun Zicheng Wang X. Zhang
+ PDF Chat	Inferring Drug-induced Plasticity via Drug Screen Data	2024	Chenyu Wu Einar Bjarki Gunnarsson Jasmine Foo Kevin Leder
+ PDF Chat	Novel Optimization Techniques for Parameter Estimation	2024	Chenyu Wu Nuozhou Wang Casey Garner Kevin Leder Shuzhong Zhang
+ PDF Chat	Prediction of cancer dynamics under treatment using Bayesian neural networks: A simulated study	2024	Even Moa Myklebust Arnoldo Frigessi Fredrik Schjesvold Jasmine Foo Kevin Leder Alvaro Köhn‐Luque
+ PDF Chat	Parameter Estimation from Single Patient, Single Time-Point Sequencing Data of Recurrent Tumors	2024	Kevin Leder Ruping Sun Zicheng Wang Xuanming Zhang
+ PDF Chat	Dynamics of Advantageous Mutant Spread in Spatial Death-Birth and Birth-Death Moran Models	2023	Jasmine Foo Einar Bjarki Gunnarsson Kevin Leder David Sivakoff
+ PDF Chat	Statistical inference of the rates of cell proliferation and phenotypic switching in cancer	2023	Einar Bjarki Gunnarsson Jasmine Foo Kevin Leder
+	Supplemental Information from Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach	2023	Marc D. Ryser Walter T. Lee Neal Ready Kevin Leder Jasmine Foo
+	Supplemental Information from Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach	2023	Marc D. Ryser Walter T. Lee Neal Ready Kevin Leder Jasmine Foo
+	Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data	2023	Alvaro Köhn‐Luque Even Moa Myklebust Dagim Shiferaw Tadele Mariaserena Giliberto Leonard Schmiester Jasmine Noory Elise Harivel Polina Arsenteva Shannon M. Mumenthaler Fredrik Schjesvold
+ PDF Chat	Spread of premalignant mutant clones and cancer initiation in multilayered tissue	2023	Jasmine Foo Einar Bjarki Gunnarsson Kevin Leder Kathleen M. Storey
+	Limit theorems for the site frequency spectrum of neutral mutations in an exponentially growing population	2023	Einar Bjarki Gunnarsson Kevin Leder Xuanming Zhang
+	Using birth-death processes to infer tumor subpopulation structure from live-cell imaging drug screening data	2023	Chengbiao Wu E. B. Gunnarsson Even Moa Myklebust Alvaro Köhn‐Luque Dagim Shiferaw Tadele Jorrit Martijn Enserink Arnoldo Frigessi Jasmine Foo Kevin Leder
+ PDF Chat	Statistical inference of the rates of cell proliferation and phenotypic switching in cancer	2022	Einar Bjarki Gunnarsson Jasmine Foo Kevin Leder
+ PDF Chat	Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data	2022	Alvaro Köhn‐Luque Even Moa Myklebust Dagim Shiferaw Tadele Mariaserena Giliberto Leonard Schmiester Jasmine Noory Elise Harivel Polina Arsenteva Shannon M. Mumenthaler Fredrik Schjesvold
+ PDF Chat	Large deviations of cancer recurrence timing	2022	Pranav Hanagal Kevin Leder Zicheng Wang
+	Dynamics of advantageous mutant spread in spatial death-birth and birth-death Moran models	2022	Jasmine Foo Einar Bjarki Gunnarsson Kevin Leder David Sivakoff
+	Exact site frequency spectra of neutrally evolving tumors: A transition between power laws reveals a signature of cell viability	2021	Einar Bjarki Gunnarsson Kevin Leder Jasmine Foo
+	Splitting Algorithms for Rare Events of Semimartingale Reflecting Brownian Motions	2021	Kevin Leder Xin Liu Zicheng Wang
+	Clonal Diversity at Cancer Recurrence	2021	Kevin Leder Zicheng Wang
+	Mutation timing in a spatial model of evolution	2020	Jasmine Foo Kevin Leder Jason Schweinsberg
+	Understanding the role of phenotypic switching in cancer drug resistance	2020	Einar Bjarki Gunnarsson Subhajyoti De Kevin Leder Jasmine Foo
+	Mutation timing in a spatial model of evolution	2020	Jasmine Foo Kevin Leder Jason Schweinsberg
+	Large Deviations of Cancer Recurrence Timing	2020	Pranav Hanagal Kevin Leder Zicheng Wang
+	Spread of premalignant mutant clones and cancer initiation in multilayered tissue	2020	Jasmine Foo Einar Bjarki Gunnarsson Kevin Leder Kathleen M. Storey
+	Mutation timing in a spatial model of evolution	2020	Jasmine Foo Kevin Leder Jason Schweinsberg
+	Splitting Algorithms for Rare Events of Semimartingale Reflecting Brownian motions	2019	Kevin Leder Xin Liu Zicheng Wang
+	Rare-event analysis for extremal eigenvalues of white Wishart matrices	2017	Tiefeng Jiang Kevin Leder Gongjun Xu
+ PDF Chat	Optimized Treatment Schedules for Chronic Myeloid Leukemia	2016	Qie He Junfeng Zhu David Dingli Jasmine Foo Kevin Leder
+ PDF Chat	Optimal treatment and stochastic modeling of heterogeneous tumors	2016	Hamidreza Badri Kevin Leder
+ PDF Chat	A mathematical model of tumor growth and its response to single irradiation	2016	Yoichi Watanabe E Dahlman Kevin Leder Susanta Hui
+	Optimizing chemoradiotherapy to target multi-site metastatic disease and tumor growth	2016	Hamidreza Badri Ehsan Salari Yoichi Watanabe Kevin Leder
+	Additional file 2: of A mathematical model of tumor growth and its response to single irradiation	2016	Yoichi Watanabe E Dahlman Kevin Leder Susanta Hui
+	Additional file 1: of A mathematical model of tumor growth and its response to single irradiation	2016	Yoichi Watanabe E Dahlman Kevin Leder Susanta Hui
+ PDF Chat	Minimizing metastatic risk in radiotherapy fractionation schedules	2015	Hamidreza Badri Jagdish Ramakrishnan Kevin Leder
+	Spatial Moran models, II: cancer initiation in spatially structured tissue	2015	R. Durrett Jasmine Foo Kevin Leder
+	Optimization of radiation dosing schedules for proneural glioblastoma	2015	Hamidreza Badri Kenneth L. Pitter Eric C. Holland Franziska Michor Kevin Leder
+	SU‐E‐T‐751: Three‐Component Kinetic Model of Tumor Growth and Radiation Response for Stereotactic Radiosurgery	2015	Yoichi Watanabe E Dahlman Kevin Leder Susanta Hui
+	Robust optimization of dose schedules in radiotherapy	2015	Hamidreza Badri Yoichi Watanabe Kevin Leder
+	Robust and probabilistic optimization of dose schedules in radiotherapy	2015	Hamidreza Badri Yoichi Watanabe Kevin Leder
+ PDF Chat	The Impact of Microenvironmental Heterogeneity on the Evolution of Drug Resistance in Cancer Cells	2015	Shannon M. Mumenthaler Jasmine Foo Nathan C. Choi Nicholas Heise Kevin Leder David B. Agus William Pao Franziska Michor Parag Mallick
+	Spatial measures of genetic heterogeneity during carcinogenesis	2015	Kathleen M. Storey Marc D. Ryser Kevin Leder Jasmine Foo
+	A kinetic model of tumor growth and its radiation response with an application to Gamma Knife stereotactic radiosurgery	2015	Yoichi Watanabe E Dahlman Kevin Leder Susanta Hui
+	Robust and probabilistic optimization of dose schedules in radiotherapy	2015	Hamidreza Badri Yoichi Watanabe Kevin Leder
+	Rare-event Analysis for Extremal Eigenvalues of the Beta-Laguerre Ensemble	2014	Tiefeng Jiang Kevin Leder Gongjun Xu
+	Escape times for branching processes with random mutational fitness effects	2014	Jasmine Foo Kevin Leder Junfeng Zhu
+ PDF Chat	Multifocality and recurrence risk: A quantitative model of field cancerization	2014	Jasmine Foo Kevin Leder Marc D. Ryser
+ PDF Chat	Mathematical Modeling of PDGF-Driven Glioblastoma Reveals Optimized Radiation Dosing Schedules	2014	Kevin Leder Kenneth L. Pitter Quincey LaPlant Dolores Hambardzumyan Brian D. Ross Timothy A. Chan Eric C. Holland Franziska Michor
+	Rare-event Analysis for Extremal Eigenvalues of white Wishart matrices	2014	Tiefeng Jiang Kevin Leder Gongjun Xu
+	Rare-event simulation for stochastic recurrence equations with heavy-tailed innovations	2013	José Blanchet Henrik Hult Kevin Leder
+	Multifocality and recurrence risk: a quantitative model of field cancerization	2013	Jasmine Foo Kevin Leder Marc D. Ryser
+ PDF Chat	Multifocality and recurrence risk: a quantitative model of field cancerization	2013	Jasmine Foo Kevin Leder Marc D. Ryser
+ PDF Chat	Dynamics of cancer recurrence	2013	Jasmine Foo Kevin Leder
+	Multifocality and recurrence risk: a quantitative model of field cancerization	2013	Jasmine Foo Kevin Leder Marc D. Ryser
+	Rare events in cancer recurrence timing	2012	Jasmine Foo Kevin Leder
+ PDF Chat	Rare events in cancer recurrence timing	2012	Jasmine Foo Kevin Leder
+ PDF Chat	Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors	2012	Jasmine Foo Kevin Leder Shannon M. Mumenthaler
+	On Lyapunov Inequalities and Subsolutions for Efficient Importance Sampling	2012	José Blanchet Peter W. Glynn Kevin Leder
+	Importance sampling for stochastic recurrence equations with heavy tailed increments	2011	José Blanchet Henrik Hult Kevin Leder
+ PDF Chat	Analysis of a Splitting Estimator for Rare Event Probabilities in Jackson Networks	2011	José Blanchet Kevin Leder Yixi Shi
+ PDF Chat	Importance sampling for stochastic recurrence equations with heavy tailed increments	2011	José Blanchet Henrik Hult Kevin Leder
+ PDF Chat	Intratumor Heterogeneity in Evolutionary Models of Tumor Progression	2011	Rick Durrett Jasmine Foo Kevin Leder John Mayberry Franziska Michor
+ PDF Chat	Stochastic dynamics of cancer initiation	2011	Jasmine Foo Kevin Leder Franziska Michor
+	Analysis of a splitting estimator for rare event probabilities in Jackson networks	2011	José Blanchet Kevin Leder Yixi Shi
+ PDF Chat	The Therapeutic Implications of Plasticity of the Cancer Stem Cell Phenotype	2010	Kevin Leder Eric C. Holland Franziska Michor
+ PDF Chat	Evolutionary dynamics of tumor progression with random fitness values	2010	Rick Durrett Jasmine Foo Kevin Leder John Mayberry Franziska Michor
+	Analysis of a Splitting Estimator for Rare Event Probabilities in Jackson Networks	2010	José Blanchet Kevin Leder Yixi Shi
+	Importance Sampling for Weighted-Serve-the-Longest-Queue	2009	Paul Dupuis Kevin Leder Hui Wang
+	Large deviations and importance sampling for a tandem network with slow-down	2007	Paul Dupuis Kevin Leder Hui Wang

Common Coauthors

Coauthor	Papers Together
Jasmine Foo	34
Einar Bjarki Gunnarsson	10
Yoichi Watanabe	8
Hamidreza Badri	7
José Blanchet	7
Marc D. Ryser	7
Franziska Michor	7
Susanta Hui	5
E Dahlman	5
Even Moa Myklebust	4
Arnoldo Frigessi	4
Shannon M. Mumenthaler	4
Alvaro Köhn‐Luque	4
Zicheng Wang	3
Gongjun Xu	3
Tiefeng Jiang	3
Henrik Hult	3
Jason Schweinsberg	3
Fredrik Schjesvold	3
Dagim Shiferaw Tadele	3
Yixi Shi	3
Kathleen M. Storey	3
Zicheng Wang	3
Neal Ready	2
Paul Dupuis	2
Rick Durrett	2
John Mayberry	2
Polina Arsenteva	2
Junfeng Zhu	2
Mariaserena Giliberto	2
Pranav Hanagal	2
Walter T. Lee	2
Kjetil Taskén	2
David Sivakoff	2
Kenneth L. Pitter	2
Jasmine Noory	2
Eric C. Holland	2
Elise Harivel	2
Leonard Schmiester	2
Jorrit M. Enserink	2
Ruping Sun	2
Xuanming Zhang	2
Nathan C. Choi	1
Eric C. Holland	1
William Pao	1
Nicholas Heise	1
Peter W. Glynn	1
Brian D. Ross	1
Dolores Hambardzumyan	1
Chengbiao Wu	1

Commonly Cited References

Action	Title	Year	Authors	# of times referenced
+	Spatial Stochastic Models for Cancer Initiation and Progression	2006	Natalia L. Komarova	8
+ PDF Chat	Evolutionary dynamics of tumor progression with random fitness values	2010	Rick Durrett Jasmine Foo Kevin Leder John Mayberry Franziska Michor	8
+ PDF Chat	On the Williams-Bjerknes Tumour Growth Model I	1981	Maury Bramson David Griffeath	8
+ PDF Chat	Dynamic importance sampling for queueing networks	2007	Paul Dupuis Ali Devin Sezer Hui Wang	8
+	Subsolutions of an Isaacs Equation and Efficient Schemes for Importance Sampling	2007	Paul Dupuis Hui Wang	7
+	Stochastic modeling of drug resistance in cancer	2005	Natalia L. Komarova	7
+	A stochastic model for the origin and treatment of tumors containing drug-resistant cells	1986	Andrew J. Coldman J.H. Goldie	7
+ PDF Chat	A waiting time problem arising from the study of multi-stage carcinogenesis	2009	Rick Durrett Deena Schmidt Jason Schweinsberg	7
+ PDF Chat	Dynamics of cancer recurrence	2013	Jasmine Foo Kevin Leder	7
+ PDF Chat	Spatial Moran models I. Stochastic tunneling in the neutral case	2014	Richard Durrett Stephen Moseley	6
+ PDF Chat	Markovian paths to extinction	2007	Peter Jagers Fima C. Klebaner Serik Sagitov	6
+	Spatial Moran models, II: cancer initiation in spatially structured tissue	2015	R. Durrett Jasmine Foo Kevin Leder	6
+	Population genetics of tumor suppressor genes	2004	Yoh Iwasa Franziska Michor Natalia L. Komarova Martin A. Nowak	6
+ PDF Chat	Accumulation of driver and passenger mutations during tumor progression	2010	Ivana Božić Tibor Antal Hisashi Ohtsuki Hannah Carter Dewey Kim Sining Chen Rachel Karchin Kenneth W. Kinzler Bert Vogelstein Martin A. Nowak	6
+ PDF Chat	Efficient rare-event simulation for the maximum of heavy-tailed random walks	2008	José Blanchet Peter W. Glynn	6
+ PDF Chat	Mathematical Modeling of PDGF-Driven Glioblastoma Reveals Optimized Radiation Dosing Schedules	2014	Kevin Leder Kenneth L. Pitter Quincey LaPlant Dolores Hambardzumyan Brian D. Ross Timothy A. Chan Eric C. Holland Franziska Michor	6
+	Escape times for branching processes with random mutational fitness effects	2014	Jasmine Foo Kevin Leder Junfeng Zhu	6
+ PDF Chat	Multifocality and recurrence risk: A quantitative model of field cancerization	2014	Jasmine Foo Kevin Leder Marc D. Ryser	6
+	On Lyapunov Inequalities and Subsolutions for Efficient Importance Sampling	2012	José Blanchet Peter W. Glynn Kevin Leder	5
+	Role of optimal control theory in cancer chemotherapy	1990	George W. Swan	5
+	Branching Process Models of Cancer	2015	Richard Durrett	5
+	Importance Sampling, Large Deviations, and Differential Games	2004	Paul Dupuis Hui Wang	5
+ PDF Chat	Cancer recurrence times from a branching process model	2019	Stefano Avanzini Tibor Antal	5
+	On the Williams-Bjerknes tumour growth model: II	1980	Maury Bramson David Griffeath	5
+ PDF Chat	Analysis of an importance sampling estimator for tandem queues	1995	Paul Glasserman Shing-Gang Kou	5
+	Branching Process Models of Cancer	2015	Richard Durrett	5
+	Cancer as an evolutionary and ecological process	2006	Lauren M.F. Merlo John W. Pepper Brian J. Reid Carlo C. Maley	4
+ PDF Chat	Rare Events Simulation for Heavy-Tailed Distributions	2000	Søren Asmussen Klemens Binswanger Bjarne Højgaard Søren Asmussen Bjarne Højgaard	4
+ PDF Chat	Genetic Progression and the Waiting Time to Cancer	2007	Niko Beerenwinkel Tibor Antal David Dingli Arne Traulsen Kenneth W. Kinzler Victor E. Velculescu Bert Vogelstein Martin A. Nowak	4
+	A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.	1979	Goldie Jh Coldman Aj	4
+ PDF Chat	Spatial structure increases the waiting time for cancer	2011	Erik A. Martens Rumen Kostadinov Carlo C. Maley Oskar Hallatschek	4
+	A survey of optimization models on cancer chemotherapy treatment planning	2011	Jinghua Shi Oğuzhan Alagöz Fatih Safa Erenay Qiang Su	4
+	Quantitative model for multiple levels of drug resistance in clinical tumors.	1983	J H Goldie Andrew J. Coldman	4
+ PDF Chat	Importance Sampling in the Monte Carlo Study of Sequential Tests	1976	David Siegmund	4
+	Splitting for rare event simulation: A large deviation approach to design and analysis	2008	Thomas Dean Paul Dupuis	4
+	Mutation–selection networks of cancer initiation: tumor suppressor genes and chromosomal instability	2003	Natalia L. Komarova Anirvan M. Sengupta Martin A. Nowak	4
+	Optimization of radiation dosing schedules for proneural glioblastoma	2015	Hamidreza Badri Kenneth L. Pitter Eric C. Holland Franziska Michor Kevin Leder	4
+ PDF Chat	Traveling waves of selective sweeps	2011	Rick Durrett John Mayberry	4
+ PDF Chat	Mutation frequencies in a birth–death branching process	2018	David Cheek Tibor Antal	4
+	Spatial stochastic models of cancer: Fitness, migration, invasion	2013	Natalia L. Komarova Natalia L. Komarova	4
+ PDF Chat	Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells	2011	Piyush B. Gupta Christine M. Fillmore Guozhi Jiang Sagi Shapira Kai Tao Charlotte Kuperwasser Eric S. Lander	3
+	Fluid heuristics, Lyapunov bounds and efficient importance sampling for a heavy-tailed G/G/1 queue	2007	José Blanchet Peter W. Glynn J. C. Liu	3
+	On the path to extinction	2007	Peter Jagers Fima C. Klebaner Serik Sagitov	3
+	Evolutionary dynamics of cancer in response to targeted combination therapy	2013	Ivana Božić Johannes G. Reiter Benjamin Allen Tibor Antal Krishnendu Chatterjee Preya Shah Yo Sup Moon Amin Yaqubie Nicole Kelly Dung T. Le	3
+ PDF Chat	Evolution of Resistance to Targeted Anti-Cancer Therapies during Continuous and Pulsed Administration Strategies	2009	Jasmine Foo Franziska Michor	3
+ PDF Chat	Multitype Bienaymé–Galton–Watson processes escaping extinction	2009	Serik Sagitov Maria Conceição Serra	3
+ PDF Chat	On the distribution of the largest eigenvalue in principal components analysis	2001	Iain M. Johnstone	3
+ PDF Chat	Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition	2015	Aaron Goldman Biswanath Majumder Andrew Dhawan Sudharshan Ravi David Goldman Mohammad Kohandel Pradip K. Majumder Shiladitya Sengupta	3
+ PDF Chat	Selection in spatial stochastic models of cancer: Migration as a key modulator of fitness	2010	Craig J. Thalhauser John Lowengrub Dwayne G. Stupack Natalia L. Komarova	3
+ PDF Chat	Dynamic optimization of a linear–quadratic model with incomplete repair and volume-dependent sensitivity and repopulation	2000	Lawrence M. Wein Jonathan E. Cohen Joseph T. Wu	3