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Phenotype divergence and cooperation in isogenic multicellularity and in cancer
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2024
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Frank Ernesto Alvarez
Jean Clairambault
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Mathematical Modelling of Cancer Growth and Drug Treatments: Taking Into Account Cell Population Heterogeneity and Plasticity
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2023
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Jean Clairambault
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Supplementary Material, Tables S1-S2 and Figures S1-S7 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Data from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Supplementary Movie 3 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Supplementary Movie 2 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Data from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Supplementary Material, Tables S1-S2 and Figures S1-S7 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Supplementary Movie 3 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Supplementary Movie 2 from Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2023
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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A phenotype-structured model for the tumour-immune response
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2023
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Zineb Kaid
Camille Pouchol
Jean Clairambault
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Phenotype divergence and cooperation in isogenic multicellularity and in cancer
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2023
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Frank Ernesto Alvarez
Jean Clairambault
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Evolution of a structured cell population endowed with plasticity of traits under constraints on and between the traits
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2022
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Frank Ernesto Alvarez
José A. Carrillo
Jean Clairambault
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Perspectives in cancer treatment
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2022
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Maxim Kuznetsov
Jean Clairambault
Vitaly Volpert
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Perspectives in cancer treatment. Reply to comments on "Improving cancer treatments via dynamical biophysical models"
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2022
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Maxim Kuznetsov
Jean Clairambault
Vitali Volpert
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Improving cancer treatments via dynamical biophysical models
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2021
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Maxim Kuznetsov
Jean Clairambault
Vitaly Volpert
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Faculty Opinions recommendation of Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells.
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2020
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Jean Clairambault
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Plasticity in Cancer Cell Populations: Biology, Mathematics and Philosophy of Cancer
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2020
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Jean Clairambault
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A survey of adaptive cell population dynamics models of emergence of drug resistance in cancer, and open questions about evolution and cancer
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2019
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Jean Clairambault
Camille Pouchol
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Adaptive dynamics of hematopoietic stem cells and their supporting stroma: a model and mathematical analysis
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2019
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Nguyen Thanh Hoai Nam
Jean Clairambault
Thierry Jaffredo
Benoı̂t Perthame
Delphine Salort
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An Evolutionary Perspective on Cancer, with Applications to Anticancer Drug Resistance Modelling and Perspectives in Therapeutic Control
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2019
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Jean Clairambault
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Introducing Cell-Plasticity Mechanisms into a Class of Cell Population Dynamical Systems
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2018
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Walid Djema
Catherine Bonnet
Frédéric Mazenc
Jean Clairambault
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Stability Analysis of a Nonlinear System with Infinite Distributed Delays Describing Cell Dynamics
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2018
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Walid Djema
Frédéric Mazenc
Catherine Bonnet
Jean Clairambault
Emilia Fridman
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Control in dormancy or eradication of cancer stem cells: Mathematical modeling and stability issues
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2018
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Walid Djema
Catherine Bonnet
Frédéric Mazenc
Jean Clairambault
Emilia Fridman
Pierre Hirsch
François Delhommeau
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Analysis of a System Describing Proliferative-Quiescent Cell Dynamics
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2018
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Jean Clairambault
Benoı̂t Perthame
Andrada Quillas Maran
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Why Is Evolution Important in Cancer and What Mathematics Should Be Used to Treat Cancer? Focus on Drug Resistance
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2018
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Luís Almeida
Rebecca H. Chisholm
Jean Clairambault
Tommaso Lorenzi
Alexander Lorz
Camille Pouchol
Emmanuel Trélat
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Asymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapy
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2017
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Camille Pouchol
Jean Clairambault
Alexander Lorz
Emmanuel Trélat
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Integrating Biological and Mathematical Models to Explain and Overcome Drug Resistance in Cancer, Part 2: from Theoretical Biology to Mathematical Models
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2017
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Aaron Goldman
Mohammad Kohandel
Jean Clairambault
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Integrating Biological and Mathematical Models to Explain and Overcome Drug Resistance in Cancer. Part 1: Biological Facts and Studies in Drug Resistance
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2017
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Aaron Goldman
Mohammad Kohandel
Jean Clairambault
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Analysis of a model of dormancy in cancer as a state of coexistence between tumor and healthy stem cells
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2017
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Walid Djema
Catherine Bonnet
Jean Clairambault
Frédéric Mazenc
Pierre Hirsch
François Delhommeau
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Stability of a delay system coupled to a differential-difference system describing the coexistence of ordinary and mutated hematopoietic stem cells
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2016
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Walid Djema
Frédéric Mazenc
Catherine Bonnet
Jean Clairambault
Pierre Hirsch
François Delhommeau
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Tracking the evolution of cancer cell populations through the mathematical lens of phenotype-structured equations
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2016
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Tommaso Lorenzi
Rebecca H. Chisholm
Jean Clairambault
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Tumour growth and drug resistance: an evolutionary view with perspectives in therapeutics
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2016
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Jean Clairambault
Luís Almeida
Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Benoı̂t Perthame
Camille Pouchol
Emmanuel Trélat
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PDF
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Cell population heterogeneity and evolution towards drug resistance in cancer: Biological and mathematical assessment, theoretical treatment optimisation
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2016
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Rebecca H. Chisholm
Tommaso Lorenzi
Jean Clairambault
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Physiologically Structured Cell Population Dynamic Models with Applications to Combined Drug Delivery Optimisation in Oncology
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2016
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Jean Clairambault
Olivier Fercoq
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Preface of the “Symposium on Mathematical Models and Methods to investigate Heterogeneity in Cell and Cell Population Biology”
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2016
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Jean Clairambault
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Phenotype heterogeneity in cancer cell populations
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2016
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Luís Almeida
Rebecca H. Chisholm
Jean Clairambault
Alexandre E. Escargueil
Tommaso Lorenzi
Alexander Lorz
Emmanuel Trélat
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Emergence of cytotoxic resistance in cancer cell populations: Single-cell mechanisms and population-level consequences
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2016
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Tommaso Lorenzi
Rebecca H. Chisholm
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Mathematics of Pharmacokinetics and Pharmacodynamics: Diversity of Topics, Models and Methods
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2016
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Gennady Bocharov
Anass Bouchnita
Jean Clairambault
Vitaly Volpert
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Asymptotic analysis and optimal control of an integro-differential system modelling healthy and cancer cells exposed to chemotherapy
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2016
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Camille Pouchol
Jean Clairambault
Alexander Lorz
Emmanuel Trélat
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PDF
Chat
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Preface to Session 70 " Mathematical models and methods to investigate heterogeneity in cell and cell population biology "
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2015
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Loïc Barbarroux
Jean Clairambault
N. G. Cogan
J. E. Elias
Shalla Hanson
Marek Kimmel
Tommaso Lorenzi
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Phenotype heterogeneity in cancer cell populations
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2015
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Luís Almeida
Rebecca H. Chisholm
Jean Clairambault
Alexandre E. Escargueil
Tommaso Lorenzi
Alexander Lorz
Emmanuel Trélat
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Emergence of Drug Tolerance in Cancer Cell Populations: An Evolutionary Outcome of Selection, Nongenetic Instability, and Stress-Induced Adaptation
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2015
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Rebecca H. Chisholm
Tommaso Lorenzi
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
|
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PDF
Chat
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Emergence of cytotoxic resistance in cancer cell populations*
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2015
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Tommaso Lorenzi
Rebecca H. Chisholm
Alexander Lorz
Annette K. Larsen
Luís Almeida
Alexandre E. Escargueil
Jean Clairambault
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Modeling the Effects of Space Structure and Combination Therapies on Phenotypic Heterogeneity and Drug Resistance in Solid Tumors
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2014
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Alexander Lorz
Tommaso Lorenzi
Jean Clairambault
Alexandre E. Escargueil
Benoı̂t Perthame
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Enabling multiscale modeling in systems medicine: From reactions in cells to organ physiology
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2014
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Olaf Wolkenhauer
Charles Auffray
Olivier Brass
Jean Clairambault
Andreas Deutsch
Dirk Drasdo
Francesco Luigi Gervasio
Luigi Preziosi
Philip K. Maini
Anna Marciniak‐Czochra
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Deterministic Mathematical Modelling for Cancer Chronotherapeutics: Cell Population Dynamics and Treatment Optimization
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2014
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Jean Clairambault
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Deterministic mathematical modelling for cancer chronotherapeutics: cell population dynamics and treatment optimisation
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2013
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Jean Clairambault
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Effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
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2013
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Alexander Lorz
Tommaso Lorenzi
Jean Clairambault
Alexandre E. Escargueil
Benoı̂t Perthame
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Designing proliferating cell population models with functional targets for control by anti-cancer drugs
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2013
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Frédérique Billy
Jean Clairambault
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Pharmacokinetic Modeling
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2013
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Jean Clairambault
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Age-structured cell population model to study the influence of growth factors on cell cycle dynamics
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2012
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Frédérique Billy
Jean Clairambault
Franck Delaunay
Céline Feillet
Natalia Robert
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Applying ecological and evolutionary theory to cancer: a long and winding road
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2012
|
Frédéric Thomas
Daniel Fisher
Philippe Fort
Jean‐Pierre Marie
Simon P. Daoust
Benjamín Roche
Christoph Grunau
Céline Cosseau
Guillaume Mitta
Stephen Baghdiguian
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Optimisation of Cancer Drug Treatments Using Cell Population Dynamics
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2012
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Frédérique Billy
Jean Clairambault
Olivier Fercoq
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Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
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2012
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Alexander Lorz
Tommaso Lorenzi
Michael Hochberg
Jean Clairambault
Benoı̂t Perthame
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Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
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2012
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Alexander Lorz
Tommaso Lorenzi
Michael Hochberg
Jean Clairambault
Benoı̂t Perthame
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Can theorems help treat cancer?
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2012
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Jean Clairambault
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Modelling targets for anticancer drug control optimization in physiologically structured cell population models
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2012
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Frédérique Billy
Jean Clairambault
Olivier Fercoq
Tommaso Lorenzi
Alexander Lorz
Benoı̂t Perthame
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Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
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2012
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Alexander Lorz
Tommaso Lorenzi
Michael Hochberg
Jean Clairambault
Benoı̂t Perthame
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Local Asymptotic Stability Conditions for the Positive Equilibrium of a System Modeling Cell Dynamics in Leukemia
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2012
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Hitay Özbay
Catherine Bonnet
Houda Benjelloun
Jean Clairambault
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Optimizing cancer pharmacotherapeutics using mathematical modeling and a systems biology approach
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2011
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Jean Clairambault
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Proliferation in Cell Population Models with Age Structure
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2011
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Frédérique Billy
Jean Clairambault
Olivier Fercoq
Stéphane Gaubert
Thomas Lepoutre
Thomas Ouillon
Theodore E. Simos
George Psihoyios
Ch. Tsitouras
Zacharias Anastassi
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Modélisation biomédicale : Vers une médecine personnalisée
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2010
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Jean Clairambault
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Circadian rhythm and cell population growth
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2010
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Jean Clairambault
Stéphane Gaubert
Thomas Lepoutre
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Modelling the spatial organization of cell proliferation in the developing central nervous system
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2010
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Jean Clairambault
Vladimir Flores
Benoı̂t Perthame
Melina Rapacioli
Edmundo Rofman
Rafael Verdes
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Modelling the genesis and treatment of cancer: The potential role of physiologically based pharmacodynamics
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2009
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Jean‐Louis Steimer
Svein G. Dahl
Dinesh P. de Alwis
Ursula Gundert‐Remy
Mats O. Karlsson
Jiřina Martı́nková
Leon Aarons
Hans-Jürgen Ahr
Jean Clairambault
Gilles Freyer
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Faculty Opinions recommendation of Dynamics and potential impact of the immune response to chronic myelogenous leukemia.
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2009
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Jean Clairambault
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Modelling Physiological and Pharmacological Control on Cell Proliferation to Optimise Cancer Treatments
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2009
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Jean Clairambault
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Comparison of Perron and Floquet Eigenvalues in Age Structured Cell Division Cycle Models
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2009
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Jean Clairambault
Stéphane Gaubert
Thomas Lepoutre
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Modélisation de la dynamique de l'hématopoïèse normale et pathologique Modelling the dynamics of normal and pathological haematopoiesis
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2008
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Mostafa Adimy
Samuel Bernard
Jean Clairambault
Fabien Crauste
Stéphane Génieys
Laurent Pujo-Menjouet
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An inequality for the Perron and Floquet eigenvalues of monotone differential systems and age structured equations
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2007
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Jean Clairambault
Stéphane Gaubert
Benoı̂t Perthame
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Analysis of a molecular structured population model with possible polynomial growth for the cell division cycle
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2007
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Fadia Bekkal Brikci
Jean Clairambault
Benoı̂t Perthame
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Modeling oxaliplatin drug delivery to circadian rhythms in drug metabolism and host tolerance
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2007
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Jean Clairambault
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A Mathematical Model of the Cell Cycle and Its Circadian Control
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2007
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Jean Clairambault
Philippe Michel
Benoı̂t Perthame
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Circadian rhythm and tumour growth
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2006
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Jean Clairambault
Philippe Michel
Benoı̂t Perthame
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New Results - Autres applications de la théorie de Perron-Frobenius non-linéaire/Other applications of non-linear Perron-Frobenius theory
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2006
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Marianne Akian
Stéphane Gaubert
Laure Ninove
Jean Clairambault
Benoı̂t Perthame
Edurne Seijo
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An age-and-cyclin-structured cell population model with proliferation and quiescence for healthy and tumoral tissues
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2006
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Fadia Bekkal Brikci
Jean Clairambault
Benjamin Ribba
Benoı̂t Perthame
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Rythme circadien et croissance tumorale
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2006
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Jean Clairambault
Philippe Michel
Benoı̂t Perthame
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Circadian rhythm and tumour growth
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2005
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Jean Clairambault
Philippe Michel
Benoı̂t Perthame
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Optimisation of time-scheduled regimen for anti-cancer drug infusion
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2005
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Claude Basdevant
Jean Clairambault
Françis Lévi
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Optimal drug infusion strategies for cancer chronotherapy
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2004
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Claude Basdevant
Jean Clairambault
Françis Lévi
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Toxicité et efficacité antitumorale de l'oxaliplatine sur l'ostéosarcome de Glasgow induit chez la souris : un modèle mathématique
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2003
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Jean Clairambault
Claude Daniel
Elisabeth Filipski
Teresa Granda
Françis Lévi
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A mathematical model of the cell cycle and its control
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2003
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Jean Clairambault
Béatrice Laroche
Stéphane Mischler
Benoı̂t Perthame
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