A Regulatory View on Adaptive/Flexible Clinical Trial Design

Hung Hung, Robert T. O’Neill, Sue‐Jane Wang, John Lawrence

Type: Article

Publication Date: 2006-06-13

Citations: 73

DOI: https://doi.org/10.1002/bimj.200610229

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Biometrical Journal - View
PubMed - View

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+	Potential of adaptive clinical trial designs in pharmacogenetic research	2012	Frederieke H. van der Baan Mirjam J. Knol Olaf H. Klungel Toine C. G. Egberts Diederick E. Grobbee Kit CB Roes
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+	A Bootstrap Procedure for Adaptive Selection of the Test Statistic in Flexible Two-Stage DesignsThis paper is based on a presentation given at the Workshop “Frontiers in Adaptive Designs”, 17.–18. 5. 2001, Vienna/Austria.	2002	Meinhard Kieser Brit Schneider Tim Friede
+	Recursive Combination Tests	2002	Werner Brannath Martin Posch Péter Bauer
+	Self-designing clinical trials	1998	Lloyd D. Fisher
+	Combining different phases in the development of medical treatments within a single trial	1999	Péter Bauer Meinhard Kieser
+	Designed Extension of Studies Based on Conditional Power	1995	Michael A. Proschan Sally Hunsberger
+	Statistical Inference for Self‐Designing Clinical Trials with a One‐Sided Hypothesis	1999	Yu Shen Lloyd D. Fisher
+	Design of clinical trials using an adaptive test statistic	2002	John Lawrence
+	Nonparametric Estimation of a Delay Distribution Based on Left‐Censored and Right‐Truncated Data	1999	Jisheng Cui
+	Adaptive Two Stage Designs and the Conditional Error Function	1999	Martin Posch Péter Bauer
+	An adaptive method for establishing a dose‐response relationship	1995	Péter Bauer Joachim Röhmel