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Bit reset protocols that obey activity-constrained speed limits do not
minimize work for a given speed
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2025
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Daan Mulder
Thomas E. Ouldridge
Pieter Rein ten Wolde
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Autonomous learning of generative models with chemical reaction network ensembles
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2025
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William Poole
Thomas E. Ouldridge
Manoj Gopalkrishnan
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Is stochastic thermodynamics the key to understanding the energy costs of computation?
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2024
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David H. Wolpert
Jan Korbel
Christopher W. Lynn
Farita Tasnim
Joshua A. Grochow
GĂŒlce KardeĆ
James B. Aimone
Vijay Balasubramanian
Eric DeGiuli
David Doty
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The Interplay of Heterogeneity and Product Detachment in Templated
Polymer Copying
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2024
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Jeremy E. B. Guntoro
Benjamin J. Qureshi
Thomas E. Ouldridge
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Pipelined information flow in molecular mechanical circuits leads to increased error and irreversibility
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2024
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Ian Seet
Thomas E. Ouldridge
Jonathan P. K. Doye
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PDF
Chat
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Recurrent neural chemical reaction networks that approximate arbitrary
dynamics
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2024
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Alexander Dack
Benjamin Qureshi
Thomas E. Ouldridge
Tomislav Plesa
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PDF
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Information propagation in far-from-equilibrium molecular templating
networks is optimised by pseudo-equilibrium systems with negligible
dissipation
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2024
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Benjamin Qureshi
Jenny M. Poulton
Thomas E. Ouldridge
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PDF
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Thermodynamics of deterministic finite automata operating locally and periodically
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2023
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Thomas E. Ouldridge
David H. Wolpert
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PDF
Chat
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Simulation of reversible molecular mechanical logic gates and circuits
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2023
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Ian Seet
Thomas E. Ouldridge
Jonathan P. K. Doye
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+
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Pipelined information flow in molecular mechanical circuits leads to increased error and irreversibility
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2023
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Ian Seet
Thomas E. Ouldridge
Jonathan P. K. Doye
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+
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Autonomous Learning of Generative Models with Chemical Reaction Network Ensembles
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2023
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William Poole
Thomas E. Ouldridge
Manoj Gopalkrishnan
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+
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Is stochastic thermodynamics the key to understanding the energy costs of computation?
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2023
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David H. Wolpert
Jan Korbel
Christopher W. Lynn
Farita Tasnim
Joshua A. Grochow
GĂŒlce KardeĆ
James B. Aimone
Vijay Balasubramanian
Eric DeGiuli
David Doty
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+
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Exploiting bias in optimal finite-time copying protocols
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2023
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Daan Mulder
Pieter Rein ten Wolde
Thomas E. Ouldridge
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PDF
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Minimal mechanism for cyclic templating of length-controlled copolymers under isothermal conditions
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2022
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Jordan Juritz
Jenny M. Poulton
Thomas E. Ouldridge
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PDF
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Free energy landscapes of DNA and its assemblies: perspectives from coarse-grained modelling
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2022
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Jonathan P. K. Doye
Ard A. Louis
John S. Schreck
Flavio Romano
Ryan M. Harrison
Majid Mosayebi
Megan C. Engel
Thomas E. Ouldridge
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Simulation of reversible molecular mechanical logic gates and circuits
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2022
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Ian Seet
Thomas E. Ouldridge
Jonathan P. K. Doye
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Detailed Balanced Chemical Reaction Networks as Generalized Boltzmann Machines
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2022
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William Poole
Thomas E. Ouldridge
Manoj Gopalkrishnan
Erik Winfree
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Thermodynamics of deterministic finite automata operating locally and periodically
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2022
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Thomas E. Ouldridge
David H. Wolpert
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+
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A Universal Method for Analysing Copolymer Growth
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2022
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Benjamin J. Qureshi
Jordan Juritz
Jenny M. Poulton
Adrian Beersing-Vasquez
Thomas E. Ouldridge
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PDF
Chat
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Free-energy landscapes of DNA and its assemblies: Perspectives from
coarse-grained modelling
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2021
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Jonathan P. K. Doye
Ard A. Louis
John S. Schreck
Flavio Romano
Ryan M. Harrison
Majid Mosayebi
Megan C. Engel
Thomas E. Ouldridge
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PDF
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A Primer on the oxDNA Model of DNA: When to Use it, How to Simulate it and How to Interpret the Results
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2021
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Aditya Sengar
Thomas E. Ouldridge
Oliver Henrich
Lorenzo Rovigatti
Petr Ć ulc
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Edge-effects dominate copying thermodynamics for finite-length molecular oligomers
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2021
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Jenny M. Poulton
Thomas E. Ouldridge
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+
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oxDNA simulation setup files
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2021
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Aditya Sengar
Thomas E. Ouldridge
Lorenzo Rovigatti
Oliver Henrich
Petr Ć ulc
Flavio Romano
Jonathan P. K. Doye
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oxDNA simulation setup files
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2021
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Aditya Sengar
Thomas E. Ouldridge
Lorenzo Rovigatti
Oliver Henrich
Petr Ć ulc
Flavio Romano
Jonathan P. K. Doye
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What would it take to build a thermodynamically reversible Universal Turing machine? Computational and thermodynamic constraints in a molecular design
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2021
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Rory A. Brittain
Nick S. Jones
Thomas E. Ouldridge
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Integral feedback in synthetic biology: Negative-equilibrium catastrophe
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2021
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Tomislav Plesa
Alex Dack
Thomas E. Ouldridge
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PDF
Chat
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Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration
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2020
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Abhishek Deshpande
Thomas E. Ouldridge
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Implementing Non-Equilibrium Networks with Active Circuits of Duplex Catalysts
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2020
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Antti Lankinen
Ismael Mullor Ruiz
Thomas E. Ouldridge
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Robust control of biochemical reaction networks via stochastic morphing
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2019
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Tomislav Plesa
GuyâBart Stan
Thomas E. Ouldridge
Wooli Bae
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PDF
Chat
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Identifying Physical Causes of Apparent Enhanced Cyclization of Short DNA Molecules with a Coarse-Grained Model
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2019
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Ryan M. Harrison
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
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PDF
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The Power of Being Explicit: Demystifying Work, Heat, and Free Energy in the Physics of Computation
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2019
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Thomas E. Ouldridge
Rory A. Brittain
Pieter Rein ten Wolde
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PDF
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Physical Limitations of Work Extraction from Temporal Correlations
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2019
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Elan Stopnitzky
Susanne Still
Thomas E. Ouldridge
Lee Altenberg
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PDF
Chat
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Biochemical Szilard engines for memory-limited inference
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2019
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Rory A. Brittain
Nick S. Jones
Thomas E. Ouldridge
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Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration
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2019
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Abhishek Deshpande
Thomas E. Ouldridge
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+
PDF
Chat
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Physical limitations of work extraction from temporal correlations
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2019
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Elan Stopnitzky
Susanne Still
Thomas E. Ouldridge
Lee Altenberg
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+
PDF
Chat
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Nonequilibrium correlations in minimal dynamical models of polymer copying
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2019
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Jenny M. Poulton
Pieter Rein ten Wolde
Thomas E. Ouldridge
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+
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Robust control of biochemical reaction networks via stochastic morphing
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2019
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Tomislav Plesa
GuyâBart Stan
Thomas E. Ouldridge
Wooli Bae
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+
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Optimizing enzymatic catalysts for rapid turnover of substrates with low enzyme sequestration
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2019
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Abhishek Deshpande
Thomas E. Ouldridge
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+
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Initialization files and data supporting https://arxiv.org/abs/1506.09008
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2018
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Ryan M. Harrison
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
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+
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Initialization files and data supporting https://arxiv.org/abs/1506.09008
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2018
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Ryan M. Harrison
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
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Dummy Upload For Arxiv:1506.09008 Supplementary Data
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2018
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Thomas E. Ouldridge
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Dummy Upload For Arxiv:1506.09008 Supplementary Data
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2018
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Thomas E. Ouldridge
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+
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Non-equilibrium correlations in minimal dynamical models of polymer copying
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2018
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Jenny M. Poulton
Pieter Rein ten Wolde
Thomas E. Ouldridge
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+
PDF
Chat
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Coarse-grained simulation of DNA using LAMMPS
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2018
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Oliver Henrich
Yair Augusto Gutiérrez Fosado
Tine Curk
Thomas E. Ouldridge
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PDF
Chat
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Multi-scale coarse-graining for the study of assembly pathways in DNA-brick self-assembly
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2018
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Pedro Fonseca
Flavio Romano
John S. Schreck
Thomas E. Ouldridge
Jonathan P. K. Doye
Ard A. Louis
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+
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The power of being explicit: demystifying work, heat, and free energy in the physics of computation
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2018
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Thomas E. Ouldridge
Rory A. Brittain
Pieter Rein ten Wolde
|
+
PDF
Chat
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Geometric integrator for Langevin systems with quaternion-based rotational degrees of freedom and hydrodynamic interactions
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2017
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Ruslan L. Davidchack
Thomas E. Ouldridge
M. V. Tretyakov
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PDF
Chat
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The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics
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2017
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Thomas E. Ouldridge
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PDF
Chat
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High rates of fuel consumption are not required by insulating motifs to suppress retroactivity in biochemical circuits
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2017
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Abhishek Deshpande
Thomas E. Ouldridge
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High rates of fuel consumption are not required by insulating motifs to suppress retroactivity in biochemical circuits
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2017
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Abhishek Deshpande
Thomas E. Ouldridge
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+
PDF
Chat
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Designing the optimal bit: balancing energetic cost, speed and reliability
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2017
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Abhishek Deshpande
Manoj Gopalkrishnan
Thomas E. Ouldridge
Nick S. Jones
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+
PDF
Chat
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What we learn from the learning rate
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2017
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Rory A. Brittain
Nick S. Jones
Thomas E. Ouldridge
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+
PDF
Chat
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Fundamental Costs in the Production and Destruction of Persistent Polymer Copies
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2017
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Thomas E. Ouldridge
Pieter Rein ten Wolde
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+
PDF
Chat
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Thermodynamics of Computational Copying in Biochemical Systems
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2017
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Thomas E. Ouldridge
Christopher C. Govern
Pieter Rein ten Wolde
|
+
PDF
Chat
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Multiscale simulations of anisotropic particles combining molecular dynamics and Greenâs function reaction dynamics
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2017
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Adithya Vijaykumar
Thomas E. Ouldridge
Pieter Rein ten Wolde
Peter G. Bolhuis
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The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics
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2017
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Thomas E. Ouldridge
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PDF
Chat
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Biochemical Machines for the Interconversion of Mutual Information and Work
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2017
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Thomas McGrath
Nick S. Jones
Pieter Rein ten Wolde
Thomas E. Ouldridge
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PDF
Chat
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Chemical Boltzmann Machines
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2017
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William Poole
Andrés Ortiz-Muñoz
Abhishek Behera
Nick S. Jones
Thomas E. Ouldridge
Erik Winfree
Manoj Gopalkrishnan
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+
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The importance of thermodynamics for molecular systems, and the importance of molecular systems for thermodynamics
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2017
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Thomas E. Ouldridge
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+
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High rates of fuel consumption are not required by insulating motifs to suppress retroactivity in biochemical circuits
|
2017
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Abhishek Deshpande
Thomas E. Ouldridge
|
+
PDF
Chat
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Force-Induced Rupture of a DNA Duplex: From Fundamentals to Force Sensors
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2015
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Majid Mosayebi
Ard A. Louis
Jonathan P. K. Doye
Thomas E. Ouldridge
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+
PDF
Chat
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Modelling DNA origami self-assembly at the domain level
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2015
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Frits Dannenberg
Katherine E. Dunn
Jonathan Bath
Marta Kwiatkowska
Andrew J. Turberfield
Thomas E. Ouldridge
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Coarse-grained modelling of strong DNA bending II: Cyclization
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2015
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Ryan M. Harrison
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
|
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PDF
Chat
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Introducing improved structural properties and salt dependence into a coarse-grained model of DNA
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2015
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Benedict Snodin
Ferdinando Randisi
Majid Mosayebi
Petr Ć ulc
John S. Schreck
Flavio Romano
Thomas E. Ouldridge
Roman Tsukanov
Eyal Nir
Ard A. Louis
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+
PDF
Chat
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DNA hairpins destabilize duplexes primarily by promoting melting rather than by inhibiting hybridization
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2015
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John S. Schreck
Thomas E. Ouldridge
Flavio Romano
Petr Ć ulc
Liam P. Shaw
Ard A. Louis
Jonathan P. K. Doye
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PDF
Chat
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Characterizing the bending and flexibility induced by bulges in DNA duplexes
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2015
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John S. Schreck
Thomas E. Ouldridge
Flavio Romano
Ard A. Louis
Jonathan P. K. Doye
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PDF
Chat
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New Langevin and gradient thermostats for rigid body dynamics
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2015
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Ruslan L. Davidchack
Thomas E. Ouldridge
M. V. Tretyakov
|
+
PDF
Chat
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Modelling Toehold-Mediated RNA Strand Displacement
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2015
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Petr Ć ulc
Thomas E. Ouldridge
Flavio Romano
Jonathan P. K. Doye
Ard A. Louis
|
+
PDF
Chat
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Plectoneme tip bubbles: Coupled denaturation and writhing in supercoiled DNA
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2015
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Christian Matek
Thomas E. Ouldridge
Jonathan P. K. Doye
Ard A. Louis
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Fundamental Limits to Cellular Sensing
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2015
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Pieter Rein ten Wolde
Nils B. Becker
Thomas E. Ouldridge
Andrew Mugler
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Coarse-grained modelling of strong DNA bending I: Thermodynamics and comparison to an experimental "molecular vice"
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2015
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Ryan M. Harrison
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
|
+
PDF
Chat
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DNA nanotechnology: understanding and optimisation through simulation
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2014
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Thomas E. Ouldridge
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+
PDF
Chat
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The Role of Loop Stacking in the Dynamics of DNA Hairpin Formation
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2014
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Majid Mosayebi
Flavio Romano
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
|
+
PDF
Chat
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The Robustness of Proofreading to Crowding-Induced Pseudo-Processivity in the MAPK Pathway
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2014
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Thomas E. Ouldridge
Pieter Rein ten Wolde
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PDF
Chat
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A nucleotide-level coarse-grained model of RNA
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2014
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Petr Ć ulc
Flavio Romano
Thomas E. Ouldridge
Jonathan P. K. Doye
Ard A. Louis
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On the Connection between Computational and Biochemical Measurement
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2014
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Thomas E. Ouldridge
Christopher C. Govern
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+
PDF
Chat
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Simulating a burnt-bridges DNA motor with a coarse-grained DNA model
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2013
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Petr Ć ulc
Thomas E. Ouldridge
Flavio Romano
Jonathan P. K. Doye
Ard A. Louis
|
+
PDF
Chat
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DNA hybridization kinetics: zippering, internal displacement and sequence dependence
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2013
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Thomas E. Ouldridge
Petr Ć ulc
Flavio Romano
Jonathan P. K. Doye
Ard A. Louis
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+
PDF
Chat
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Coarse-grained simulations of DNA overstretching
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2013
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Flavio Romano
Debayan Chakraborty
Jonathan P. K. Doye
Thomas E. Ouldridge
Ard A. Louis
|
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PDF
Chat
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Coarse-graining DNA for simulations of DNA nanotechnology
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2013
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Jonathan P. K. Doye
Thomas E. Ouldridge
Ard A. Louis
Flavio Romano
Petr Ć ulc
Christian Matek
Benedict Snodin
Lorenzo Rovigatti
John S. Schreck
Ryan M. Harrison
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+
PDF
Chat
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Inferring bulk self-assembly properties from simulations of small systems with multiple constituent species and small systems in the grand canonical ensemble
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2012
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Thomas E. Ouldridge
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+
PDF
Chat
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Sequence-dependent thermodynamics of a coarse-grained DNA model
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2012
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Petr Ć ulc
Flavio Romano
Thomas E. Ouldridge
Lorenzo Rovigatti
Jonathan P. K. Doye
Ard A. Louis
|
+
PDF
Chat
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DNA Cruciform Arms Nucleate through a Correlated but Asynchronous Cooperative Mechanism
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2012
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Christian Matek
Thomas E. Ouldridge
Adam Levy
Jonathan P. K. Doye
Ard A. Louis
|
+
PDF
Chat
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The effect of topology on the structure and free energy landscape of DNA kissing complexes
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2012
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Flavio Romano
Alexander Hudson
Jonathan P. K. Doye
Thomas E. Ouldridge
Ard A. Louis
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+
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Inferring bulk self-assembly properties from small simulations: multiple constituent species and systems in the grand canonical ensemble
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2012
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Thomas E. Ouldridge
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+
PDF
Chat
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Structural, mechanical, and thermodynamic properties of a coarse-grained DNA model
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2011
|
Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
|
+
PDF
Chat
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DNA Nanotweezers Studied with a Coarse-Grained Model of DNA
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2010
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Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
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+
PDF
Chat
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Extracting bulk properties of self-assembling systems from small simulations
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2010
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Thomas E. Ouldridge
Ard A. Louis
Jonathan P. K. Doye
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PDF
Chat
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The self-assembly of DNA Holliday junctions studied with a minimal model
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2009
|
Thomas E. Ouldridge
Iain G. Johnston
Ard A. Louis
Jonathan P. K. Doye
|