Nancy Flournoy

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All published works

Action	Title	Year	Authors
+	Influence of the slope in percentile estimation through binary regression for dose-finding experiments	2024	Nancy Flournoy José Antonio Moler Maider Sada
+	The cost of sequential adaptation and the lower bound for mean squared error	2024	Sergey Tarima Nancy Flournoy
+ PDF Chat	Bayesian and Frequentist Approaches to Rescuing Disrupted Trials: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2024	Cornelia Ursula Kunz Sergey Tarima Gary L. Rosner Richard Emsley Madeline Bauer Christopher Jennison James L. Rosenberger Nigel Stallard Sarah Zohar Nancy Flournoy
+	Estimation of the Emax model	2024	Giacomo Aletti Nancy Flournoy Caterina May Chiara Tommasi
+	Up-and-Down: The Most Popular, Most Reliable, and Most Overlooked Dose-Finding Design	2024	Assaf P. Oron Nancy Flournoy
+	Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2023	Silvia Calderazzo Sergey Tarima Carissa Reid Nancy Flournoy Tim Friede Nancy L. Geller James L. Rosenberger Nigel Stallard Moreno Ursino Marc Vandemeulebroecke
+	Posterior alternatives with informative early stopping	2023	Nancy Flournoy Sergey Tarima
+	Group sequential tests: beyond exponential family models	2023	Sergey Tarima Nancy Flournoy
+	On dose-response modeling for evaluation of drugs combinations	2023	Nancy Flournoy Leonard B. Hearne Jozef Kiseľák Milan Stehlík
+	Rejoinder: Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2023	Kelly Van Lancker Sergey Tarima Jonathan Bartlett Madeline Bauer Bharani Bharani-Dharan Frank Bretz Nancy Flournoy Hege Michiels Camila Olarte Parra James L. Rosenberger
+	The NISS Ingram Olkin Forum on Unplanned Clinical Trial Disruptions	2023	Nancy Flournoy
+	Design Considerations for Two-Stage Enrichment Clinical Trials	2022	Rosamarie Frieri William F. Rosenberger Nancy Flournoy Zhantao Lin
+	Understanding Research Methods: Up-and-down Designs for Dose-finding	2022	Assaf P. Oron Michael J. Souter Nancy Flournoy
+ PDF Chat	Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2022	Kelly Van Lancker Sergey Tarima Jonathan Bartlett Madeline Bauer Bharani Bharani-Dharan Frank Bretz Nancy Flournoy Hege Michiels Camila Olarte Parra James L. Rosenberger
+	Discussion on “Adaptive enrichment designs with a continuous biomarker” by Nigel Stallard	2022	Nancy Flournoy Sergey Tarima
+	Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2022	Kelly Van Lancker Sergey Tarima Jonathan Bartlett Madeline Bauer Bharani Bharani-Dharan Frank Bretz Nancy Flournoy Hege Michiels Camila Olarte Parra James L. Rosenberger
+	Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions	2022	Silvia Calderazzo Sergey Tarima Carissa Reid Nancy Flournoy Tim Friede Nancy L. Geller James L. Rosenberger Nigel Stallard Moreno Ursino Marc Vandemeulebroecke
+	The Cost of Sequential Adaptation and the Lower Bound for Mean Squared Error	2022	Sergey Tarima Nancy Flournoy
+	Inference for a two-stage enrichment design	2021	Zhantao Lin Nancy Flournoy William F. Rosenberger
+	Most powerful test sequences with early stopping options	2021	Sergey Tarima Nancy Flournoy
+ PDF Chat	Choosing Interim Sample Sizes in Group Sequential Designs	2021	Sergey Tarima Nancy Flournoy
+	The effects of adaptation on maximum likelihood inference for nonlinear models with normal errors	2021	Nancy Flournoy Caterina May Chiara Tommasi
+	Most Powerful Test Sequences with Early Stopping Options	2021	Sergey Tarima Nancy Flournoy
+	Most Powerful Test Sequences with Early Stopping Options	2021	Sergey Tarima Nancy Flournoy
+ PDF Chat	Performance Measures in Dose‐Finding Experiments	2020	Nancy Flournoy José Antonio Moler Fernando Plo
+	Distribution theory following blinded and unblinded sample size re-estimation under parametric models	2019	Sergey Tarima Nancy Flournoy
+ PDF Chat	Random norming aids analysis of non-linear regression models with sequential informative dose selection	2019	Zhantao Lin Nancy Flournoy William F. Rosenberger
+	Bias induced by adaptive dose-finding designs	2019	Nancy Flournoy Assaf P. Oron
+	Asymptotic properties of maximum likelihood estimators with sample size recalculation	2019	Sergey Tarima Nancy Flournoy
+	Random Norming Aids Analysis of Non-linear Regression Models with Sequential Informative Dose Selection	2019	Zhantao Lin Nancy Flournoy William F. Rosenberger
+	Effect of Interim Adaptations in Group Sequential Designs	2019	Sergey Tarima Nancy Flournoy
+	The Effects of Adaptation on Inference for Non-Linear Regression Models with Normal Errors	2018	Nancy Flournoy Caterina May Chiara Tommasi
+ PDF Chat	Centered Isotonic Regression: Point and Interval Estimation for Dose–Response Studies	2017	Assaf P. Oron Nancy Flournoy
+	Centered Isotonic Regression: Point and Interval Estimation for Dose-Response Studies	2017	Assaf P. Oron Nancy Flournoy
+ PDF Chat	A Ballooned Beta-Logistic Model	2017	Min Yi Nancy Flournoy Eloi Kpamegan
+	Centered Isotonic Regression: Point and Interval Estimation for Dose-Response Studies	2017	Assaf P. Oron Nancy Flournoy
+	A BIRTH AND DEATH URN FOR RANDOMIZED CLINICAL TRIALS: ASYMPTOTIC METHODS	2016	Anastasia Ivanova William F. Rosenberger S. D. Durham Nancy Flournoy
+	Conditional Inference in Two-Stage Adaptive Experiments via the Bootstrap	2016	Adam Lane HaiYing Wang Nancy Flournoy
+	Up-and-Down Designs for Dose-Finding	2015	Nancy Flournoy Assaf P. Oron
+	On the consistency of the maximum likelihood estimator for the three parameter lognormal distribution	2015	HaiYing Wang Nancy Flournoy
+	The focused information criterion for varying-coefficient partially linear measurement error models	2014	Hai Ying Wang Xinjie Chen Nancy Flournoy
+	Up‐and‐Down Designs	2014	Nancy Flournoy Assaf P. Oron
+	A graphical comparison of response-adaptive randomization procedures	2014	Nancy Flournoy Linda M. Haines William F. Rosenberger
+	A new bounded log-linear regression model	2013	HaiYing Wang Nancy Flournoy Eloi Kpamegan
+	Optimal designs for contingent response models with application to toxicity–efficacy studies	2013	Huwaida Rabie Nancy Flournoy
+	A Graphical Comparison of Response-Adaptive Randomization Procedures	2013	Nancy Flournoy Linda M. Haines William F. Rosenberger
+	Randomization Based Inference for the Drop-The-Loser Rule	2013	Nancy Flournoy Arkaitz Galbete José Antonio Moler Fernando Plo
+	Up‐and‐Down Designs	2012	Nancy Flournoy Assaf P. Oron
+	Adaptive Designs	2012	Nancy Flournoy Assaf P. Oron
+	Asymptotically Optimal Response‐Adaptive Designs for Allocating the Best Treatment: An Overview	2012	Nancy Flournoy Caterina May Piercesare Secchi
+	University of Missouri Department of Statistics	2012	Nancy Flournoy Melody Galen
+	2011 Summer School on Statistical Experimental	2011	Nancy Flournoy
+	Optimal designs for response functions with a downturn	2010	Seung Won Hyun Min Yang Nancy Flournoy
+	On Testing Hypotheses in Response-Adaptive Designs Targeting the Best Treatment	2010	Nancy Flournoy Caterina May José Antonio Moler Fernando Plo
+	Information in a Two-stage Adaptive Optimal Design for Normal Random Variables having a One Parameter Exponential Mean Function	2010	Ping Yao Nancy Flournoy
+ PDF Chat	Asymptotics in response-adaptive designs generated by a two-color, randomly reinforced urn	2009	Caterina May Nancy Flournoy
+ PDF Chat	Comparison of Isotonic Designs for Dose-Finding	2009	Anastasia Ivanova Nancy Flournoy
+ PDF Chat	Up-and-Down Designs for Selecting the Dose with Maximum Success Probability	2008	Euloge E. Kpamegan Nancy Flournoy
+ PDF Chat	A New Tool for Comparing Adaptive Designs; a Posteriori Efficiency	2007	José Antonio Moler Nancy Flournoy
+	Phase I Clinical Trials	2007	Anastasia Ivanova Nancy Flournoy
+ PDF Chat	Evaluation of development traits of beef buffalo in Brazil using multivariate analysis	2007	Júlio César de Souza A. A. Ramos Carlos Henrique Mendes Malhado André Mendes Jorge Paulo Bahiense Ferraz Filho J.A. DeFreitas Nancy Flournoy W. R. Lamberson
+	Cumulative cohort design for dose-finding	2006	Anastasia Ivanova Nancy Flournoy Yeonseung Chung
+	Group Up‐and‐Down Designs in Toxicity Studies	2006	Anna Ivanova Nancy Flournoy
+	Preface	2005	Nancy Flournoy W.F. Rosenberger
+	Group up-and-down designs for dose-finding	2005	Misrak Gezmu Nancy Flournoy
+	Quantile estimation following non‐parametric phase I clinical trials with ordinal response	2004	Ranjan Kumar Paul William F. Rosenberger Nancy Flournoy
+	Additive Hazards Model for Competing Risks Analysis of the Case-Cohort Design	2004	Jianguo Sun Liuquan Sun Nancy Flournoy
+	Estimating the probability of toxicity at the target dose following an up‐and‐down design	2003	Mario Stylianou Michael A. Proschan Nancy Flournoy
+	RESPONSE-DRIVEN URN DESIGNS: COMMENT ON “RANDOMIZED URN MODELS AND SEQUENTIAL DESIGN” BY W. F. ROSENBERGER	2002	Nancy Flournoy
+	Dose Finding Using the Biased Coin Up‐and‐Down Design and Isotonic Regression	2002	Mario Stylianou Nancy Flournoy
+	Up‐and‐Down Designs	2001	Nancy Flournoy
+	Adaptive Designs	2001	Nancy Flournoy
+	An Optimizing Up-and-Down Design	2001	Euloge E. Kpamegan Nancy Flournoy
+	Multivariate Optimizing Up and Down Design	2001	Nawar Shara Nancy Flournoy
+	A sequential design for maximizing the probability of a favourable response	1998	S. D. Durham Nancy Flournoy W. Li
+ PDF Chat	Exact Distributions of Sequential Threshold Estimators	1998	Nancy Flournoy Douglas G. Kelly
+ PDF Chat	Restricted optimality for phase I clinical trials	1998	Vladimir A. Mats William F. Rosenberger Nancy Flournoy
+	A Random Walk Rule for Phase I Clinical Trials	1997	S. D. Durham Nancy Flournoy William F. Rosenberger
+	Asymptotic normality of maximum likelihood estimators from multiparameter response-driven designs	1997	William F. Rosenberger Nancy Flournoy S. D. Durham
+ PDF Chat	Up-and-down designs. II. Exact treatment moments	1995	S. D. Durham Nancy Flournoy Ali A. Montazer-Haghighi
+ PDF Chat	Up-and-down designs. I. Stationary treatment distributions	1995	S. D. Durham Nancy Flournoy
+ PDF Chat	An adaptive design for maximization of a contingent binary response	1995	Zhengqing Li S. D. Durham Nancy Flournoy
+	Toxicity in sequential dose-response experiments	1995	Nancy Flournoy S. D. Durham William F. Rosenberger
+	Random Walks for Quantile Estimation	1994	S. D. Durham Nancy Flournoy
+	Statistical Multiple Integration.	1993	H. N. Nancy Flournoy Robert K. Tsutakawa
+	Convergence Results for an Adaptive Ordinal Urn Design	1993	S. D. Durham Nancy Flournoy
+	A Clinical Experiment in Bone Marrow Transplantation: Estimating a Percentage Point of a Quantal Response Curve	1993	Nancy Flournoy
+	Analysis of Trials with Treatment — Individual Interactions	1992	Jack Cuzick B Domínguez Trejo Nancy Flournoy Peter Sasieni
+	Estimating Random Effects In the Framingham Heart Study	1992	John P. Klein Melvin L. Moeschberger Y. H. Li Shuai Wang Nancy Flournoy
+	Assessment of Dependence In the Life Times of Twins	1992	Philip Hougaard B Harvald Niels V. Holm Nancy Flournoy M. Ataharul Islam Kalpana Singh
+	Statistical Multiple Integration	1991	Nancy Flournoy Robert K. Tsutakawa
+	Dependency in multivariate markov chains	1990	Nancy Flournoy
+	Adaptive Sampling Designs.	1989	Nancy Flournoy
+	The Analysis of Failure Times in the Presence of Competing Risks	1978	Ross L. Prentice John D. Kalbfleisch Arthur V. Peterson Nancy Flournoy Vernon T. Farewell N. E. Breslow

Common Coauthors

Coauthor	Papers Together
Sergey Tarima	18
William F. Rosenberger	12
S. D. Durham	10
Assaf P. Oron	10
Caterina May	6
James L. Rosenberger	6
Kelly Van Lancker	5
José Antonio Moler	5
Zhantao Lin	4
Anastasia Ivanova	4
Madeline Bauer	4
Jonathan Bartlett	3
Suzie Cro	3
Hege Michiels	3
Frank Bretz	3
Camila Olarte Parra	3
Chiara Tommasi	3
Fernando Plo	3
Nigel Stallard	3
HaiYing Wang	3
Sarah Zohar	3
Bharani Bharani-Dharan	3
Linda M. Haines	2
Mario Stylianou	2
Nancy L. Geller	2
Moreno Ursino	2
Tim Friede	2
Silvia Calderazzo	2
Carissa Reid	2
Marc Vandemeulebroecke	2
Robert K. Tsutakawa	2
Eloi Kpamegan	2
Euloge E. Kpamegan	2
Carlos Henrique Mendes Malhado	1
J.A. DeFreitas	1
Xinjie Chen	1
Richard Emsley	1
Ross L. Prentice	1
Vernon T. Farewell	1
Júlio César de Souza	1
Adam Lane	1
Shuai Wang	1
H. N.	1
Vladimir A. Mats	1
Jozef Kiseľák	1
A. A. Ramos	1
John D. Kalbfleisch	1
André Mendes Jorge	1
Michael J. Souter	1
Zhengqing Li	1

Commonly Cited References

Action	Title	Year	Authors	# of times referenced
+	Random Walks for Quantile Estimation	1994	S. D. Durham Nancy Flournoy	21
+	A sequential design for maximizing the probability of a favourable response	1998	S. D. Durham Nancy Flournoy W. Li	15
+ PDF Chat	Up-and-down designs. I. Stationary treatment distributions	1995	S. D. Durham Nancy Flournoy	14
+	Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer	1990	John O’Quigley Margaret S. Pepe Lloyd D. Fisher	14
+ PDF Chat	Up-and-down designs. II. Exact treatment moments	1995	S. D. Durham Nancy Flournoy Ali A. Montazer-Haghighi	12
+	Properties of frequency distributions induced by general ‘up-and-down’ methods for estimating quantiles	1998	Alessandra Giovagnoli Nicolò Pintacuda	12
+	A Random Walk Rule for Phase I Clinical Trials	1997	S. D. Durham Nancy Flournoy William F. Rosenberger	11
+ PDF Chat	Asymptotics in response-adaptive designs generated by a two-color, randomly reinforced urn	2009	Caterina May Nancy Flournoy	10
+	Random Walk Design in Bio-Assay	1967	Robert K. Tsutakawa	10
+	Dose Finding Using the Biased Coin Up‐and‐Down Design and Isotonic Regression	2002	Mario Stylianou Nancy Flournoy	10
+	A BIRTH AND DEATH URN FOR RANDOMIZED CLINICAL TRIALS: ASYMPTOTIC METHODS	2016	Anastasia Ivanova William F. Rosenberger S. D. Durham Nancy Flournoy	9
+	Toxicity in sequential dose-response experiments	1995	Nancy Flournoy S. D. Durham William F. Rosenberger	9
+	Efficient Sequential Designs with Binary Data	1985	Changbao Wu	9
+	Asymptotic properties of maximum likelihood estimators with sample size recalculation	2019	Sergey Tarima Nancy Flournoy	9
+	Improved up‐and‐down designs for phase I trials	2002	Anastasia Ivanova A. Montazer-Haghighi Sri Gopal Mohanty S. D. Durham	8
+	The <i>k</i>‐in‐a‐row up‐and‐down design, revisited	2009	Assaf P. Oron Peter D. Hoff	8
+	Adaptive designs for selecting drug combinations based on efficacy–toxicity response	2007	Vladimir Dragalin Valerii V. Fedorov Yuehui Wu	7
+	Design and Analysis of Phase I Clinical Trials	1989	Barry E. Storer	7
+	A Course in Large Sample Theory	2017	Thomas S. Ferguson	7
+	Asymptotic normality of maximum likelihood estimators from multiparameter response-driven designs	1997	William F. Rosenberger Nancy Flournoy S. D. Durham	7
+	Order Restricted Statistical Inference.	1990	Thomas J. Santner Tim Robertson F. T. Wright R. L. Dykstra	7
+	The Up-and-Down Method for Small Samples	1965	W. J. Dixon	7
+	A Course in Large Sample Theory	1996	Thomas S. Ferguson	6
+	Efficient Sequential Designs With Binary Data	1985	Chi‐Fang Wu	6
+	Most powerful test sequences with early stopping options	2021	Sergey Tarima Nancy Flournoy	6
+	On the Existence of Maximum Likelihood Estimators for the Binomial Response Models	1981	Mervyn J. Silvapulle	6
+	The Theory of Response‐Adaptive Randomization in Clinical Trials	2006	Feifang Hu William F. Rosenberger	6
+	Randomized Play-the-Leader Rules for Sequential Sampling from Two Populations	1990	S. D. Durham Kaizhi Yu	6
+	Maximum Likelihood Estimation for Dependent Observations	1976	M. J. Crowder	6
+	A comparison of two phase I trial designs	1994	Edward L. Korn Douglas Midthune T. Timothy Chen Larry Rubinstein Michaele C. Christian Richard Simon	6
+	Group sequential methods in the design and analysis of clinical trials	1977	Stuart J. Pocock	6
+	A Clinical Experiment in Bone Marrow Transplantation: Estimating a Percentage Point of a Quantal Response Curve	1993	Nancy Flournoy	6
+	Cumulative cohort design for dose-finding	2006	Anastasia Ivanova Nancy Flournoy Yeonseung Chung	6
+	The Randomized Play-the-Winner Rule in Medical Trials	1978	L. J. Wei S. D. Durham	6
+	Bias reduction of maximum likelihood estimates	1993	David Firth	5
+	Group Sequential Methods with Applications to Clinical Trials	1999	Christopher Jennison Bruce W. Turnbull	5
+	Group up-and-down designs for dose-finding	2005	Misrak Gezmu Nancy Flournoy	5
+	Response‐Adaptive Randomization for Clinical Trials with Continuous Outcomes	2005	Lanju Zhang William F. Rosenberger	5
+	Assessing the accuracy of the maximum likelihood estimator: Observed versus expected Fisher information	1978	Bradley Efron D. V. Hinkley	5
+	Randomization in Clinical Trials	2002	William F. Rosenberger John M. Lachin	5
+	Up-and-down experiments of first and second order	2004	Paola Bortot Alessandra Giovagnoli	5
+	Optimality, Variability, Power	2003	Feifang Hu William F. Rosenberger	5
+	Forcing a sequential experiment to be balanced	1971	Bradley Efron	5
+	Sequential Methods in Statistics.	1987	Bob Peters G. Barrie Wetherill K. D. Glazebrook	5
+	Unbiased estimation following a group sequential test	1999	Aiyi Liu	5
+	Convergence Results for an Adaptive Ordinal Urn Design	1993	S. D. Durham Nancy Flournoy	5
+	An Optimizing Up-and-Down Design	2001	Euloge E. Kpamegan Nancy Flournoy	5
+	Repeated Significance Tests on Accumulating Data	1969	P. Armitage C. K. McPherson Beverley Charles Rowe	5
+	A randomly reinforced urn	2005	Pietro Muliere Anna Maria Paganoni Piercesare Secchi	5
+	Estimating the probability of toxicity at the target dose following an up‐and‐down design	2003	Mario Stylianou Michael A. Proschan Nancy Flournoy	5