A mathematical model of CAR-T cell therapy in combination with
chemotherapy for malignant gliomas
A mathematical model of CAR-T cell therapy in combination with
chemotherapy for malignant gliomas
We study the dynamics and interactions between combined chemotherapy and chimeric antigen receptor (CAR-T) cells therapy and malignant gliomas (MG). MG is one of the most common primary brain tumor, with high resistance to therapy and unfavorable prognosis. Here, we develop a mathematical model that describes the application of chemo- …