An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding
An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding
Ligand-receptor interactions are fundamental to many biological processes. For example in antibody-based immunotherapies, the dynamics of an antibody binding with its target antigen directly influence the potency and efficacy of monoclonal antibody (mAb) therapies. In this paper, we present an asymptotic analysis of an ordinary differential equation (ODE) model of …