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Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning.

Rapid response to fast viral evolution using AlphaFold 3-assisted topological deep learning.

The fast evolution of SARS-CoV-2 and other infectious viruses poses a grand challenge to the rapid response in terms of viral tracking, diagnostics, and design and manufacture of monoclonal antibodies (mAbs) and vaccines, which are both time-consuming and costly. This underscores the need for efficient computational approaches. Recent advancements, like …