Pushing the Boundaries: Interferometric Mass Photometry at the Quantum
Limit of Sensitivity
Pushing the Boundaries: Interferometric Mass Photometry at the Quantum
Limit of Sensitivity
We present an innovative optical imaging system for measuring parameters of a small particle such as a macromolecule or nanoparticle at the quantum limit of sensitivity. In comparison to the conventional confocal interferometric scattering (iSCAT) approach, our setup adds a second arm to form a Michelson interferometer that allows us …