Understanding how chromatin folding and enzyme competition affect rugged
epigenetic landscapes
Understanding how chromatin folding and enzyme competition affect rugged
epigenetic landscapes
Epigenetics plays a key role in cellular differentiation and maintaining cell identity, enabling cells to regulate their genetic activity without altering the DNA sequence. Epigenetic regulation occurs within the context of hierarchically folded chromatin, yet the interplay between the dynamics of epigenetic modifications and chromatin architecture remains poorly understood. In …