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Best of two worlds: Cartesian sampling and volume computation for distance-constrained configuration spaces using Cayley coordinates

Best of two worlds: Cartesian sampling and volume computation for distance-constrained configuration spaces using Cayley coordinates

Volume calculation of configurational spaces acts as a vital part in configurational entropy calculation, which contributes towards calculating free energy landscape for molecular systems. In this article, we present our sampling-based volume computation method using distance-based Cayley coordinate, mitigating drawbacks: our method guarantees that the sampling procedure stays in lower-dimensional …