Single-cell 3D genome reconstruction in the haploid setting using
rigidity theory
Single-cell 3D genome reconstruction in the haploid setting using
rigidity theory
This article considers the problem of 3-dimensional genome reconstruction for single-cell data, and the uniqueness of such reconstructions in the setting of haploid organisms. We consider multiple graph models as representations of this problem, and use techniques from graph rigidity theory to determine identifiability. Biologically, our models come from Hi-C …