Voltage mapping in subcellular nanodomains using electro-diffusion modeling
Voltage mapping in subcellular nanodomains using electro-diffusion modeling
Voltage distribution in sub-cellular micro-domains such as neuronal synapses, small protrusions or dendritic spines regulates the opening and closing of ionic channels, energy production and thus cellular homeostasis and excitability. Yet how voltage changes at such a small scale in vivo remains challenging due to the experimental diffraction limit, large …