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From Theory to Therapy: Reframing SBDD Model Evaluation via Practical Metrics

From Theory to Therapy: Reframing SBDD Model Evaluation via Practical Metrics

Recent advancements in structure-based drug design (SBDD) have significantly enhanced the efficiency and precision of drug discovery by generating molecules tailored to bind specific protein pockets. Despite these technological strides, their practical application in real-world drug development remains challenging due to the complexities of synthesizing and testing these molecules. The …