Reducing phenotype-structured PDE models of cancer evolution to systems
of ODEs: a generalised moment dynamics approach
Reducing phenotype-structured PDE models of cancer evolution to systems
of ODEs: a generalised moment dynamics approach
Intratumour phenotypic heterogeneity is nowadays understood to play a critical role in disease progression and treatment failure. Accordingly, there has been increasing interest in the development of mathematical models capable of capturing its role in cancer cell adaptation. This can be systematically achieved by means of models comprising phenotype-structured nonlocal …