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Parameter identifiability and model selection for partial differential equation models of cell invasion

Parameter identifiability and model selection for partial differential equation models of cell invasion

When employing mechanistic models to study biological phenomena, practical parameter identifiability is important for making accurate predictions across wide ranges of unseen scenarios, as well as for understanding the underlying mechanisms. In this work, we use a profile-likelihood approach to investigate parameter identifiability for four extensions of the Fisher–Kolmogorov–Petrovsky–Piskunov (Fisher–KPP) …