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AI-Aristotle: A physics-informed framework for systems biology gray-box identification

AI-Aristotle: A physics-informed framework for systems biology gray-box identification

Discovering mathematical equations that govern physical and biological systems from observed data is a fundamental challenge in scientific research. We present a new physics-informed framework for parameter estimation and missing physics identification (gray-box) in the field of Systems Biology. The proposed framework—named AI-Aristotle—combines the eXtreme Theory of Functional Connections (X-TFC) …