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Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation

Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation

Introduction Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological challenges. Conventionally, reinfection is defined as a positive test occurring at least 90 days after a previous infection diagnosis. Yet, this extended time window may …