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Caduceus: Bi-Directional Equivariant Long-Range DNA Sequence Modeling

Caduceus: Bi-Directional Equivariant Long-Range DNA Sequence Modeling

Large-scale sequence modeling has sparked rapid advances that now extend into biology and genomics. However, modeling genomic sequences introduces challenges such as the need to model long-range token interactions, the effects of upstream and downstream regions of the genome, and the reverse complementarity (RC) of DNA. Here, we propose an …