Constructing universal phenomenology for biological cellular systems: an idiosyncratic review on evolutionary dimensional reduction
Constructing universal phenomenology for biological cellular systems: an idiosyncratic review on evolutionary dimensional reduction
Abstract The possibility of establishing a macroscopic phenomenological theory for biological systems, akin to the well-established framework of thermodynamics, is briefly reviewed. We introduce the concept of an evolutionary fluctuation–response relationship, which highlights the tight correlation between the variance in phenotypic traits caused by genetic mutations and by internal noise. …