To tweak or not to tweak. How exploiting flexibilities in gene set
analysis leads to over-optimism
To tweak or not to tweak. How exploiting flexibilities in gene set
analysis leads to over-optimism
Gene set analysis, a popular approach for analysing high-throughput gene expression data, aims to identify sets of genes that show enriched expression patterns between two conditions. In addition to the multitude of methods available for this task, users are typically left with many options when creating the required input and …