Multi-omics Sampling-based Graph Transformer for Synthetic Lethality Prediction
Multi-omics Sampling-based Graph Transformer for Synthetic Lethality Prediction
Synthetic lethality (SL) prediction is used to identify if the co-mutation of two genes results in cell death. The prevalent strategy is to abstract SL prediction as an edge classification task on gene nodes within SL data and achieve it through graph neural networks (GNNs). However, GNNs suffer from limitations …