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Evolutionary shaping of low-dimensional path facilitates robust and plastic switching between phenotypes

Evolutionary shaping of low-dimensional path facilitates robust and plastic switching between phenotypes

Biological systems must be robust for stable functioning against perturbations, but robustness alone is insufficient. The ability to switch between appropriate states (phenotypes) in response to different conditions is essential for biological functions, as observed in allosteric enzymes and motor proteins. How are robustness and plasticity simultaneously acquired through evolution? …