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Analysis of two binomial proportions in noninferiority confirmatory trials

Analysis of two binomial proportions in noninferiority confirmatory trials

Abstract In this article, we propose considering an approximate exact score (AES) test for noninferiority comparisons and we derive its test‐based confidence interval for the difference between two independent binomial proportions. This test was published in the literature, but not its associated confidence interval. The p ‐value for this test …