Computational modeling of angiogenesis: The importance of cell rearrangements during vascular growth
Computational modeling of angiogenesis: The importance of cell rearrangements during vascular growth
Angiogenesis is the process wherein endothelial cells (ECs) form sprouts that elongate from the pre-existing vasculature to create new vascular networks. In addition to its essential role in normal development, angiogenesis plays a vital role in pathologies such as cancer, diabetes and atherosclerosis. Mathematical and computational modeling has contributed to …