Confidence interval comparison: Precision of maximum likelihood estimates in LLOQ affected data
Confidence interval comparison: Precision of maximum likelihood estimates in LLOQ affected data
When data is derived under a single or multiple lower limits of quantification (LLOQ), estimation of distribution parameters as well as precision of these estimates appear to be challenging, as the way to account for unquantifiable observations due to LLOQs needs particular attention. The aim of this investigation is to …