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Estimation of vaccine effectiveness against SARS-CoV-2-associated hospitalisation using sentinel surveillance in South Africa, a test-negative case-control study
Abstract Background COVID-19 vaccine effectiveness (VE) studies leveraging systematic surveillance in sub-Saharan Africa are limited. We aimed to assess BNT162b2 and Ad26.COV2.S VE against SARS-CoV-2-associated hospitalisation in South African individuals aged ≥ 18 years. Methods We conducted a test-negative case-control study to estimate VE against hospitalisation in individuals enrolled in …