Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
Macrophage Anti-inflammatory Behaviour in a Multiphase Model of Atherosclerotic Plaque Development
Abstract Atherosclerosis is an inflammatory disease characterised by the formation of plaques, which are deposits of lipids and cholesterol-laden macrophages that form in the artery wall. The inflammation is often non-resolving, due in large part to changes in normal macrophage anti-inflammatory behaviour that are induced by the toxic plaque microenvironment. …