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An Improved Parameterization Procedure for NDDO-Descendant Semiempirical Methods

An Improved Parameterization Procedure for NDDO-Descendant Semiempirical Methods

Abstract MNDO-based semiempirical methods in quantum chemistry have found widespread application in the modelling of large and complex systems. A method for the analytic evaluation of first and second derivatives of molecular properties against semiempirical parameters in MNDO-based NDDO-descendant models is presented, and the resultant parameter Hessian is compared against …