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Planning preclinical confirmatory multicenter trials to strengthen translation from basic to clinical research โ a multi-stakeholder workshop report
Abstract Clinical translation from bench to bedside often remains challenging even despite promising preclinical evidence. Among many drivers like biological complexity or poorly understood disease pathology, preclinical evidence often lacks desired robustness. Reasons include low sample sizes, selective reporting, publication bias, and consequently inflated effect sizes. In this context, there โฆ