Sequential Bayes Factors for Sample Size Reduction in Preclinical Experiments with Binary Outcomes
Sequential Bayes Factors for Sample Size Reduction in Preclinical Experiments with Binary Outcomes
Preclinical studies are an integral part of pharmaceutical drug development, yet traditional methods for designing and analyzing these types of studies can be inefficient and wasteful. Even worse, when the units of study are animals, ethical concerns can arise. The 3Rs initiative was established for the ethical treatment of animals …