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The decline of COVID-19 severity and lethality over two years of pandemic

The decline of COVID-19 severity and lethality over two years of pandemic

Abstract Undernotification of SARS-CoV-2 infections has been a major obstacle to the tracking of critical quantities such as infection attack rates and the probability of severe and lethal outcomes. We use a model of SARS-CoV-2 transmission and vaccination informed by epidemiological and genomic surveillance data to estimate the number of …