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Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions

Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions

Abstract We introduce a new spatial statistic, the weighted pair correlation function (wPCF). The wPCF extends the existing pair correlation function (PCF) to describe spatial relationships between points marked with combinations of discrete and continuous labels. We validate its use through application to an agent-based model (ABM) which simulates interactions …