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Assessing the feasibility of sustaining SARS-CoV-2 local containment in China in the era of highly transmissible variants

Assessing the feasibility of sustaining SARS-CoV-2 local containment in China in the era of highly transmissible variants

We developed a spatially structured, fully stochastic, individual-based SARS-CoV-2 transmission model to evaluate the feasibility of sustaining SARS-CoV-2 local containment in mainland China considering currently dominant Omicron variants, China's current immunization level, and non-pharmaceutical interventions (NPIs). We also built a statistical model to estimate the overall disease burden under various …