Deciphering antibody affinity maturation with language models and weakly
supervised learning
Deciphering antibody affinity maturation with language models and weakly
supervised learning
In response to pathogens, the adaptive immune system generates specific antibodies that bind and neutralize foreign antigens. Understanding the composition of an individual's immune repertoire can provide insights into this process and reveal potential therapeutic antibodies. In this work, we explore the application of antibody-specific language models to aid understanding …