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Towards integration of time-resolved confocal microscopy of a 3D <i>in vitro</i> microfluidic platform with a hybrid multiscale model of tumor angiogenesis
Abstract The goal of this study is to calibrate a multiscale model of tumor angiogenesis with time-resolved data to allow for systematic testing of mathematical predictions of vascular sprouting. The multi-scale model consists of an agent-based description of tumor and endothelial cell dynamics coupled to a continuum model of vascular …