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Bayesian adaptive design of early-phase clinical trials for precision medicine based on cancer biomarkers

Bayesian adaptive design of early-phase clinical trials for precision medicine based on cancer biomarkers

Cancer tissue samples obtained via biopsy or surgery were examined for specific gene mutations by genetic testing to inform treatment. Precision medicine, which considers not only the cancer type and location, but also the genetic information, environment, and lifestyle of each patient, can be applied for disease prevention and treatment …