Making Patient-Specific Treatment Decisions Using Prognostic Variables and Utilities of Clinical Outcomes
Making Patient-Specific Treatment Decisions Using Prognostic Variables and Utilities of Clinical Outcomes
We argue that well-informed patient-specific decision-making may be carried out as three consecutive tasks: (1) estimating key parameters of a statistical model, (2) using prognostic information to convert these parameters into clinically interpretable values, and (3) specifying joint utility functions to quantify risk–benefit trade-offs between clinical outcomes. Using the management …