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Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings

Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings

Virological testing is central to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) containment, but many settings face severe limitations on testing. Group testing offers a way to increase throughput by testing pools of combined samples; however, most proposed designs have not yet addressed key concerns over sensitivity loss and implementation …