Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer
Reciprocal interactions between tumour cell populations enhance growth and reduce radiation sensitivity in prostate cancer
Abstract Intratumoural heterogeneity (ITH) contributes to local recurrence following radiotherapy in prostate cancer. Recent studies also show that ecological interactions between heterogeneous tumour cell populations can lead to resistance in chemotherapy. Here, we evaluated whether interactions between heterogenous populations could impact growth and response to radiotherapy in prostate cancer. Using …