Stages of tau aggregation associated with amyloidosis reflected in non‐negative matrix factorization components
Stages of tau aggregation associated with amyloidosis reflected in non‐negative matrix factorization components
Abstract Background Tau aggregation, when accompanied by amyloid deposition, is a key neuropathological signature of Alzheimer’s disease (AD). The regional distribution of tau may be a more sensitive marker of AD pathology than total tau level, however the spread of disease is unlikely to conform to common atlas‐based regions of …