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Validation of prognostic scoring systems for patients with metastatic renal cell carcinoma enrolled in phase I clinical trials
BackgroundFor patients with metastatic renal cell carcinoma (mRCC) who progress on standard-of-care therapies, there is an unmet need for novel treatments. Phase I clinical trials are designed to test the safety, toxicity and optimal dosing of novel agents. Herein, we analysed the outcomes of patients with mRCC enrolled in phase …