Molecular mechanisms for microtubule length regulation by kinesin-8 and XMAP215 proteins
Molecular mechanisms for microtubule length regulation by kinesin-8 and XMAP215 proteins
The cytoskeleton is regulated by a plethora of enzymes that influence the stability and dynamics of cytoskeletal filaments. How microtubules (MTs) are controlled is of particular importance for mitosis, during which dynamic MTs are responsible for proper segregation of chromosomes. Molecular motors of the kinesin-8 protein family have been shown …